Browsing Ciències Bàsiques by Subject "Receptor de progesterona"
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A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
(Cellular and Molecular Life Sciences, 2024)In hormone-responsive breast cancer cells, progesterone (P4) has been shown to act via its nuclear receptor (nPR), a ligand-activated transcription factor. A small fraction of progesterone receptor is ... -
Unliganded progesterone receptor governs estrogen receptor gene expression by regulating DNA methylation in breast cancer cells
(Cancers, 2018)Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ...