Browsing Ciències Bàsiques by Subject "6"
Now showing items 1-7 of 7
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CDKN1A/p21 in breast cancer: part of the problem, or part of the solution?
(International Journal of Molecular Sciences, 2023)Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ... -
Effects of muscarinic receptor antagonism in the basolateral amygdala on two-way active avoidance
(Experimental Brain Research, 2011)The aim of the present study was to investigate whether the blockade of muscarinic receptors (mRs) in the basolateral amygdala (BLA), which receives important cholinergic inputs related to avoidance ... -
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
(Nature Biotechnology, 2023)Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium, ... -
Muscarinic receptor blockade in ventral hippocampus and prelimbic cortex impairs memory for socially transmitted food preference
(Hippocampus, 2008)Acetylcholine is involved in learning and memory and, particularly, in olfactory tasks, but reports on its specific role in consolidation processes are somewhat controversial. The present experiment ... -
Muscarinic transmission in the basolateral amygdala is necessary for the acquisition of socially transmitted food preferences in rats
(Neurobiology of Learning and Memory, 2009)We examined the involvement of muscarinic receptors in the basolateral amygdala (BLA) in the social transmission of food preference (STFP) learning by assessing the effects of scopolamine (20 μg/side), ... -
National cultural dimensions and their impact on construction project management in developing countries: the case of Ghana
(Journal of Construction in Developing Countries, 2023)Construction project management (CPM) in developing countries (DCs) tends to experience high levels of failure. These failures have been attributed to technical, behavioural and economic factors. However, ... -
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
(Nature Communications, 2019)Manipulation of neuronal activity using two-photon excitation of azobenzene photoswitches with near-infrared light has been recently demonstrated, but their practical use in neuronal tissue to photostimulate ...