Browsing Ciències Bàsiques by Author "Wright, Roni H. G."

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    • CDKN1A/p21 in breast cancer: part of the problem, or part of the solution? 

      Manousakis, Evangelos; Martinez Miralles, Clàudia; Guimerà Esquerda, Maria; Wright, Roni H. G. (International Journal of Molecular Sciences, 2023)
      Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ...

    • A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane 

      Font Mateu, Jofre; Sanllehí, Pol; Sot, Jesús; Abad, Beatriz; Mateos, Nicolas; Torreno-Pina, Juan Andres; Ferrari, Roberto; Wright, Roni H. G.; Garcia-Parajo, Maria F.; Joglar, Jesús; Goñi, Félix M.; Beato, Miguel (Cellular and Molecular Life Sciences, 2024)
      In hormone-responsive breast cancer cells, progesterone (P4) has been shown to act via its nuclear receptor (nPR), a ligand-activated transcription factor. A small fraction of progesterone receptor is ...