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Ara mostrant els elements 49-65 de 65
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Probing RNA structural landscapes across Candida yeast genomes
(Frontiers in Microbiology, 2024)Understanding the intricate roles of RNA molecules in virulence and host-pathogen interactions can provide valuable insights into combatting infections and improving human health. Although much progress ... -
A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
(Cellular and Molecular Life Sciences, 2024)In hormone-responsive breast cancer cells, progesterone (P4) has been shown to act via its nuclear receptor (nPR), a ligand-activated transcription factor. A small fraction of progesterone receptor is ... -
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
(Nature Communications, 2019)Manipulation of neuronal activity using two-photon excitation of azobenzene photoswitches with near-infrared light has been recently demonstrated, but their practical use in neuronal tissue to photostimulate ... -
Regulation of actin dynamics during structural plasticity of dendritic spines: signaling messengers and actin-binding proteins
(Molecular and Cellular Neuroscience, 2018-09)Activity-dependent plasticity of synaptic structure and function plays an essential role in neuronal development and in cognitive functions including learning and memory. The formation, maintenance and ... -
Simplified qualitative discrete numerical model to determine cracking pattern in brittle materials by means of finite element method
(Mathematical Problems in Engineering, 2017)This paper presents the formulation, implementation, and validation of a simplified qualitative model to determine the crack path of solids considering static loads, infinitesimal strain, and plane ... -
A simplified scheme for piezoelectric anisotropic analysis in human vertebrae using integral methods
(Mathematical Problems in Engineering, 2018)This paper outlines a computational model for the analysis of the piezoelectric behaviour of the vertebral body remodelling process. Particular attention is paid to the algorithms for the simulation of ... -
Single-molecule derivation of salt dependent base-pair free energies in DNA
(Proceedings of the National Academy of Sciences., 2010)Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in ... -
Single-molecule stochastic resonance
(Physical Review X, 2012)Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ... -
Skull fractures by glass bottles tested on cadaveric heads
(International Journal of Legal Medicine, 2023)Head trauma is frequently related to the misuse of drinking vessels as weapons. Forensic reports usually evaluate these blunt injuries as having occurred in scenarios where the alcohol intake is high. ... -
Spatial control of gene expression by miR319-regulated TCP transcription factors in leaf development
(Plant Physiology, 2018)The characteristic leaf shapes we see in all plants are in good part the outcome of the combined action of several transcription factor networks that translate into cell division activity during the ... -
Statistical properties of metastable intermediates in DNA unzipping
(Physical Review Letters, 2009)We unzip DNA molecules using optical tweezers and determine the sizes of the cooperatively unzipping and zipping regions separating consecutive metastable intermediates along the unzipping pathway. Sizes ... -
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
(Computational and Structural Biotechnology Journal, 2021)Long non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated ... -
Study on balance and postural control sccording to the stabilometry in indoor skydivers: a cross-sectional study
(International Journal of Environmental Research and Public Health, 2023)Background: The wind tunnel is a compression cabin through which a stream of air rises homogeneously, generated by fans. To perform different acrobatics, indoor skydivers have to change their body ... -
SURE editing: combining oligo-recombineering and programmable insertion/deletion of selection markers to efficiently edit the Mycoplasma pneumoniae genome
(Nucleic Acids Research, 2022)The development of advanced genetic tools is boosting microbial engineering which can potentially tackle wide-ranging challenges currently faced by our society. Here we present SURE editing, a ... -
The plant noncoding transcriptome: a versatile environmental sensor
(The EMBO Journal, 2023)Plant noncoding RNA transcripts have gained increasing attention in recent years due to growing evidence that they can regulate developmental plasticity. In this review article, we comprehensively analyze ... -
Unliganded progesterone receptor governs estrogen receptor gene expression by regulating DNA methylation in breast cancer cells
(Cancers, 2018)Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ... -
Work distributions in the T = 0 random field Ising model
(Physical Review E, 2008)We perform a numerical study of the three-dimensional random-field Ising model at T= 0. We compare work distributions along metastable trajectories obtained with the single-spin flip dynamics with the ...