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dc.contributor.authorBennett, Julia C.
dc.contributor.authorHetrich, Marissa K.
dc.contributor.authorGarcia Quesada, Maria
dc.contributor.authorSinkevitch, Jenna N.
dc.contributor.authorDeloria Knoll, Maria
dc.contributor.authorFeikin, Daniel R.
dc.contributor.authorZeger, Scott L.
dc.contributor.authorKagucia, Eunice W.
dc.contributor.authorCohen, Adam L.
dc.contributor.authorAmpofo, Krow
dc.contributor.authorBrandileone, Maria-Cristina
dc.contributor.authorBruden, Dana
dc.contributor.authorCamilli, Romina
dc.contributor.authorCastilla, Jesús
dc.contributor.authorChan, Guanhao
dc.contributor.authorCook, Heather
dc.contributor.authorCornick, Jennifer E.
dc.contributor.authorDagan, Ron
dc.contributor.authorDalby, Tine
dc.contributor.authorDanis, Kostas
dc.contributor.authorDe Miguel, Sara
dc.contributor.authorDe Wals, Philippe
dc.contributor.authorDesmet, Stefanie
dc.contributor.authorGeorgakopoulou, Theano
dc.contributor.authorGilkison, Charlotte
dc.contributor.authorGrgic-Vitek, Marta
dc.contributor.authorHammitt, Laura L.
dc.contributor.authorHilty, Markus
dc.contributor.authorHo, Pak-Leung
dc.contributor.authorJayasinghe, Sanjay
dc.contributor.authorKellner, James D.
dc.contributor.authorKleynhans, Jackie
dc.contributor.authorKnol, Mirjam J.
dc.contributor.authorKozakova, Jana
dc.contributor.authorKristinsson, Karl G.
dc.contributor.authorLadhani, Shamez N.
dc.contributor.authorMacDonald, Laura
dc.contributor.authorMackenzie, Grant A.
dc.contributor.authorMad’arová, Lucia
dc.contributor.authorMcGeer, Allison
dc.contributor.authorMereckiene, Jolita
dc.contributor.authorMorfeldt, Eva
dc.contributor.authorMungun, Tuya
dc.contributor.authorMuñoz-Almagro, Carmen
dc.contributor.authorNuorti, J. Pekka
dc.contributor.authorParagi, Metka
dc.contributor.authorPilishvili, Tamara
dc.contributor.authorPuentes, Rodrigo
dc.contributor.authorSaha, Samir K.
dc.contributor.authorSahu Khan, Aalisha
dc.contributor.authorSavrasova, Larisa
dc.contributor.authorScott, J. Anthony
dc.contributor.authorSkoczynska, Anna
dc.contributor.authorSuga, Shigeru
dc.contributor.authorVan Der Linden, Mark
dc.contributor.authorVerani, Jennifer R.
dc.contributor.authorVon Gottberg, Anne
dc.contributor.authorWinje, Brita A.
dc.contributor.authorYildirim, Inci
dc.contributor.authorZerouali, Khalid
dc.contributor.authorHayford, Kyla
dc.contributor.authorPSERENADE Team
dc.date.accessioned2021-04-27T16:44:50Z
dc.date.available2021-04-27T16:44:50Z
dc.date.issued2021
dc.identifier.citationBennett, Julia C.; Hetrich, Marissa K.; Garcia Quesada, Maria [et al.]. Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project. Microorganisms, 2021, 9(4), 696. Disponible en: <https://www.mdpi.com/2076-2607/9/4/696>. Fecha de acceso: 27 abr. 2021. DOI: 10.3390/microorganisms9040696ca
dc.identifier.issn2076-2607ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/2508
dc.description.abstractStreptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST1 IPD surveillance data from sites globally and aimed to estimate PCV10/13 impact on ST1 IPD incidence. We estimated ST1 IPD incidence rate ratios (IRRs) comparing the pre-PCV10/13 period to each post-PCV10/13 year by site using a Bayesian multi-level, mixed-effects Poisson regression and all-site IRRs using a linear mixed-effects regression (N = 45 sites). Following PCV10/13 introduction, the incidence rate (IR) of ST1 IPD declined among all ages. After six years of PCV10/13 use, the all-site IRR was 0.05 (95% credibility interval 0.04–0.06) for all ages, 0.05 (0.04–0.05) for <5 years of age, 0.08 (0.06–0.09) for 5–17 years, 0.06 (0.05–0.08) for 18–49 years, 0.06 (0.05–0.07) for 50–64 years, and 0.05 (0.04–0.06) for ≥65 years. PCV10/13 use in infant immunization programs was followed by a 95% reduction in ST1 IPD in all ages after approximately 6 years. Limited data availability from the highest ST1 disease burden countries using a 3 + 0 schedule constrains generalizability and data from these settings are needed.en
dc.format.extent23ca
dc.language.isoengca
dc.publisherMDPIca
dc.relation.ispartofMicroorganismsca
dc.relation.ispartofseries9;4
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedca
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.otherVacunesca
dc.subject.otherImmunologiaca
dc.subject.otherPneumococsca
dc.subject.otherAntígensca
dc.subject.otherVacunases
dc.subject.otherInmunologíaes
dc.subject.otherStreptococcus pneumoniaees
dc.subject.otherAntígenoses
dc.subject.otherVaccinesen
dc.subject.otherImmunologyen
dc.subject.otherPneumococcusen
dc.subject.otherAntigensen
dc.titleChanges in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE projecten
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc61ca
dc.identifier.doihttps://dx.doi.org/10.3390/microorganisms9040696ca


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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/