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dc.contributor.authorHernandez, Gonzalo
dc.contributor.authorVaquero Collado, Concepción
dc.contributor.authorGarcía Plaza, Susana
dc.contributor.authorVillasclaras Pacheco, Ana
dc.contributor.authorPardo Rey, Candido
dc.contributor.authorDe la Fuente O'Connor, Eugenia
dc.contributor.authorCuena, Rafael
dc.contributor.authorGonzález Arenas, Paloma
dc.contributor.authorFernández Fernández, Rafael
dc.date.accessioned2020-02-22T16:10:45Z
dc.date.available2020-02-22T16:10:45Z
dc.date.issued2015-12-31
dc.identifier.citationHernandez, Gonzalo; Vaquero Collado, Concepción; García Plaza, Susana [et al.]. High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study. International Journal of Critical Care and Emergency Medicine, 2015, vol. 1, núm. 2, p. 1-6. Disponible en: <https://clinmedjournals.org/articles/ijccem/international-journal-of-critical-care-and-emergency-medicine-ijccem-1-009.php?jid=ijccem>. Fecha de acceso: 22 feb. 2020. DOI: 10.23937/2474-3674/1510009ca
dc.identifier.issn2474-3674ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/1463
dc.description.abstractObjective: To determine the impact of delivering high flow conditioned oxygen therapy (HFO) through nasal cannula on prevention of reintubation in mechanically ventilated (MV) critically ill patients. Design: Prospective cohort sturdy. Setting: General ICU of a university hospital. Patients: all patients under MV > 12-h and after scheduled extubation. Exclusion criteria: hypercapnia at extubation, non-scheduled extubation or with do-not-resuscitate orders. Patients were also divided between low and high reintubation risk. Interventions: From September 2011 to September 2012, all patients received HFO after extubation for a fixed 24-h period and were compared with a historical cohort (2008-2011) treated with conventional oxygen therapy and matched for risk of reintubation. Measurements and Main Results: The primary endpoint was reintubation rate within the 72-h following extubation. Statistical analyses included logistic multivariate model. Main Results: Each cohort included 111 patients with similar clinical characteristics. The HFO group showed a non-significant lower reintubation rate (8.1% vs. 15.3%, p = 0.09). Variables independently related to reintubation rate in the multivariate analysis were HFO (OR 0.31 [0.10-0.95] p = 0.04), hypercapnia after extubation (OR 51.20 [11.55-226.63] p < 0.01), APACHE II > 12 at extubation (OR 1.06 [1.01-1.12] p = 0.04) and length of MV (OR 1.16 [1.03-1.30] p =0.01). The area under the ROC curve for the model was 0.89 (0.77- 0.94). Conclusions: Routine HFO after planned extubation appears to be associated with lower reintubation rate.ca
dc.format.extent6ca
dc.language.isoengca
dc.publisherClinMed International Libraryca
dc.relation.ispartofInternational Journal of Critical Care and Emergency Medicineca
dc.relation.ispartofseries1;2
dc.rights© 2015 Hernandez G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ca
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.otherRespiració artificialca
dc.subject.otherInsuficiència respiratòria
dc.subject.otherOxigenoteràpia
dc.subject.otherRespiración artificial
dc.subject.otherInsuficiencia respiratoria
dc.subject.otherOxigenoterapia
dc.subject.otherArtificial ventilation
dc.subject.otherRespiratory failure
dc.subject.otherOxygen therapy
dc.titleHigh flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort studyca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/acceptedVersionca
dc.embargo.termscapca
dc.subject.udc61ca
dc.identifier.doihttp://dx.doi.org/10.23937/2474-3674/1510009ca


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© 2015 Hernandez G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/