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High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study
dc.contributor.author | Hernandez, Gonzalo | |
dc.contributor.author | Vaquero Collado, Concepción | |
dc.contributor.author | García Plaza, Susana | |
dc.contributor.author | Villasclaras Pacheco, Ana | |
dc.contributor.author | Pardo Rey, Candido | |
dc.contributor.author | De la Fuente O'Connor, Eugenia | |
dc.contributor.author | Cuena, Rafael | |
dc.contributor.author | González Arenas, Paloma | |
dc.contributor.author | Fernández Fernández, Rafael | |
dc.date.accessioned | 2020-02-22T16:10:45Z | |
dc.date.available | 2020-02-22T16:10:45Z | |
dc.date.issued | 2015-12-31 | |
dc.identifier.citation | Hernandez, Gonzalo; Vaquero Collado, Concepción; García Plaza, Susana [et al.]. High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study. International Journal of Critical Care and Emergency Medicine, 2015, vol. 1, núm. 2, p. 1-6. Disponible en: <https://clinmedjournals.org/articles/ijccem/international-journal-of-critical-care-and-emergency-medicine-ijccem-1-009.php?jid=ijccem>. Fecha de acceso: 22 feb. 2020. DOI: 10.23937/2474-3674/1510009 | ca |
dc.identifier.issn | 2474-3674 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/1463 | |
dc.description.abstract | Objective: To determine the impact of delivering high flow conditioned oxygen therapy (HFO) through nasal cannula on prevention of reintubation in mechanically ventilated (MV) critically ill patients. Design: Prospective cohort sturdy. Setting: General ICU of a university hospital. Patients: all patients under MV > 12-h and after scheduled extubation. Exclusion criteria: hypercapnia at extubation, non-scheduled extubation or with do-not-resuscitate orders. Patients were also divided between low and high reintubation risk. Interventions: From September 2011 to September 2012, all patients received HFO after extubation for a fixed 24-h period and were compared with a historical cohort (2008-2011) treated with conventional oxygen therapy and matched for risk of reintubation. Measurements and Main Results: The primary endpoint was reintubation rate within the 72-h following extubation. Statistical analyses included logistic multivariate model. Main Results: Each cohort included 111 patients with similar clinical characteristics. The HFO group showed a non-significant lower reintubation rate (8.1% vs. 15.3%, p = 0.09). Variables independently related to reintubation rate in the multivariate analysis were HFO (OR 0.31 [0.10-0.95] p = 0.04), hypercapnia after extubation (OR 51.20 [11.55-226.63] p < 0.01), APACHE II > 12 at extubation (OR 1.06 [1.01-1.12] p = 0.04) and length of MV (OR 1.16 [1.03-1.30] p =0.01). The area under the ROC curve for the model was 0.89 (0.77- 0.94). Conclusions: Routine HFO after planned extubation appears to be associated with lower reintubation rate. | ca |
dc.format.extent | 6 | ca |
dc.language.iso | eng | ca |
dc.publisher | ClinMed International Library | ca |
dc.relation.ispartof | International Journal of Critical Care and Emergency Medicine | ca |
dc.relation.ispartofseries | 1;2 | |
dc.rights | © 2015 Hernandez G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | ca |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject.other | Respiració artificial | ca |
dc.subject.other | Insuficiència respiratòria | |
dc.subject.other | Oxigenoteràpia | |
dc.subject.other | Respiración artificial | |
dc.subject.other | Insuficiencia respiratoria | |
dc.subject.other | Oxigenoterapia | |
dc.subject.other | Artificial ventilation | |
dc.subject.other | Respiratory failure | |
dc.subject.other | Oxygen therapy | |
dc.title | High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/acceptedVersion | ca |
dc.embargo.terms | cap | ca |
dc.subject.udc | 61 | ca |
dc.identifier.doi | http://dx.doi.org/10.23937/2474-3674/1510009 | ca |
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