Ciències de la Salut: Recent submissions
Now showing items 761-780 of 1006
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Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study
(International Journal of Infectious Diseases, 2020-08)Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ... -
Impact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental study
(Frontiers in Pharmacology, 2020-04-02)The aim of the study was to evaluate the impact of a multifaceted antimicrobial stewardship intervention on antibiotic consumption in a primary health care (PHC) area in Spain. Quasi-experimental study ... -
Applying qualitative research to develop a guide for parents of newborns with hypoxic-ischemic encephalopathy
(International Journal of Qualitative Methods, 2020-05-07)Moderate-to-severe hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal mortality and permanent disability in surviving newborns. Therapeutic hypothermia (TH) is the only effective ... -
Mimicking bone extracellular matrix: integrin-binding peptidomimetics enhance osteoblast-like cells adhesion, proliferation, and differentiation on titanium
(Colloids and Surfaces B: Biointerfaces, 2015-04-01)Interaction between the surface of implants and biological tissues is a key aspect of biomaterials research. Apart from fulfilling the non-toxicity and structural requirements, synthetic materials are ... -
Development of biomimetic NiTi alloy: influence of thermo-chemical treatment on the physical, mechanical and biological behavior
(Materials, 2016)A bioactive layer, free of nickel, has been performed for its greater acceptability and reliability in clinical applications for NiTi shape memory alloys. In the first step, a safe barrier against Ni ... -
Validation of the spanish version of the low vision quality of life questionnaire
(Journal of Optometry, 2021-04-18)Purpose: To validate the Spanish Low Vision Qualify of Life (SLVQOL) questionnaire, a quality of life instrument specifically designed for patients with visual impairment, and evaluate its psychometric ... -
Bullous henoch-schönlein purpura: a case series
(Journal of Respiratory Research, 2019-12)Henoch-Schönlein purpura (HSP) represents the most common vasculitis in children. Typically, HSP manifests with palpable purpura and edema, usually following an urticarial or erythematous maculopapular ... -
nCPAP-induced nasal injury: case series and brief literature review
(Journal of Respiratory Research, 2019-12)nCPAP-induced nose skin injury is a common issue in NICUs all over the world. Damage may vary from simple hyperemia in the region of application of nasal cannulae up to complete destruction of the ... -
Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
(Journal of Biological Chemistry, 2003-03-14)Carnitine palmitoyltransferase (CPT) I, which catalyzes the conversion of palmitoyl-CoA to palmitoylcarnitine facilitating its transport through the mitochondrial membranes, is inhibited by malonyl-CoA. ... -
Aberrantly spliced mRNAs of the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene with a donor splice-site point mutation produce hereditary HL deficiency
(Journal of Lipid Research, 1996-11)A novel point mutation in the 3-hydroxy-3methyl-glutaryl coenzyme A lyase gene was found in a Turkish patient with homozygous 3-hydroxy-3-methylglutaric acidemia. Amplification by RT-PCR of the mRNA ... -
Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle
(Journal of Biological Chemistry, 1994-04-22)The isoprenoid pathway leads to various essential non-sterol products in insects. These end products have a crucial role in growth, differentiation, sexual maturation, and reproduction. 3-Hydroxy-3-me ... -
RICH (Rapidly Involuting Congenital Hemangioma) with fetal involution
(Journal of Respiratory Research, 2019-12)A term newborn was evaluated for the presence of a lesion resembling an involuting hemangioma; dermoscopy showed some residual ectasic capillaries, consistent with the diagnosis. At 5 months, lesion ... -
N-methyl-DD-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells
(Journal of Biological Chemistry, 2006-03-10)During the postnatal development of cerebellum, lack of excitatory innervation from the mossy fibers results in cerebellar granule cell (CGC) apoptosis during the migration of the cells toward the ... -
Soluble oligomers of amyloid-β peptide disrupt Membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction
(Journal of Biological Chemistry, 2011-08-05)β-Amyloid (Aβ), a peptide generated from the amyloid precursor protein, is widely believed to underlie the pathophysiology of Alzheimer disease (AD). Emerging evidences suggest that soluble Aβ oligomers ... -
Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival
(Journal of Biological Chemistry, 2012-03-30)NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ... -
Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project
(Microorganisms, 2021)Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. ... -
The effectiveness of massage therapy for improving sequelae in post-stroke survivors. A systematic review and meta-analysis
(International Journal of Environmental Research and Public Health, 2021)Objective: To assess the effect of therapeutic massage for improving sequelae in stroke survivors. Methods: A systematic review of the nine medical databases from January 1961 to December 2020 was carried ... -
Análisis del ajuste de mascarillas autofiltrantes en combinación con las mascarillas quirúrgicas para la protección del profesional sanitario en su atención a pacientes afectos de SARS-COV-2 a partir de un estudio experimental
(Archivos de Prevención de Riesgos Laborales, 2021-04-15)Introducción: Un componente importante del equipo de protección individual (EPI) frente al SARS-CoV-2 son las mascarillas quirúrgicas y las mascarillas autofiltrantes (FFP). La norma europea EN 149 ... -
Novel regulation of the synthesis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunit gluA1 by carnitine palmitoyltransferase 1C (CPT1C) in the hippocampus
(Journal of Biological Chemistry, 2015-10-16)The regulation of AMPA-type receptor (AMPAR) abundance in the postsynaptic membrane is an important mechanism involved in learning and memory formation. Recent data suggest that one of the constituents ... -
Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation
(Journal of Biological Chemistry, 2013-02)Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ...