Ciències de la Salut: Enviaments recents
Ara mostrant els elements 381-400 de 1006
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Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays
(Nature Protocols, 2007)RNA-binding proteins (RBPs) frequently regulate the post-transcriptional fate of target mRNAs. To identify novel target mRNAs of RBPs, we incubate total RNA with recombinant RBP and immunoselect the ... -
Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype
(Hepatology International, 2018)Although guidelines are available for hereditary hemochromatosis, a high percentage of the recommendations within them are not shared between the different guidelines. Our main aim is to provide an ... -
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms
(Human Molecular Genetics, 2009)Mutations leading to abrogation of matriptase-2 proteolytic activity in humans are associated with an iron-refractory iron deficiency anemia (IRIDA) due to elevated hepcidin levels. Here we describe two ... -
Enhancing perceived leadership of nursing students through a student-led dedicated education unit in a community setting: a feasibility study
(Journal of Professional Nursing, 2022)Background: Leadership competence is important to ensure the provision of safe and high-quality care in hospitals. Purpose: The aim was to demonstrate the feasibility of enhancing the perceived leadership ... -
Incidence and reasons for intrastromal corneal ring segment explantation
(American Journal of Ophthalmology, 2021)Purpose: To determine the main causes of intrastromal corneal ring segment (ICRS) explantation and define the incidence rate. Design: Multicenter, observational consecutive case series. Methods: Consecutive ... -
Prevention of posterior capsule opacification through intracapsular hydrogen peroxide or distilled water treatment in human donor tissue
(Scientific Reports, 2018)In order to determine whether posterior capsule opacification after cataract surgery, could be delayed or inhibited through the application of hydrogen peroxide (H2O2) or distilled water (H2Od),we ... -
The effectiveness of extracorporeal shock wave therapy for improving upper limb spasticity and functionality in stroke patients: a systematic review and meta-analysis
(Clinical Rehabilitation, 2020)Objective: To assess the effectiveness of Extracorporeal Shock Wave Therapy for reducing spasticity and improving functionality of the upper limb in stroke survivors. Data sources: A systematic review ... -
The effectiveness of extracorporeal shock wave therapy to reduce lower limb spasticity in stroke patients: a systematic review and meta-analysis
(Topics in Stroke Rehabilitation, 2020)Objective: To assess the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) to reduce lower limb spasticity in adult stroke survivors. Data Sources: A systematic review of Medline/Pubmed, CENTRAL, ... -
Assessment of the 4-meter walk test test-retest reliability and concurrent validity and its correlation with the five sit-to-stand test in chronic ambulatory stroke survivors
(Gait & Posture, 2023)Background: The 4-meter walk test (4-MWT) is a widely used measure to assess gait speed in the elderly but has not been validated for stroke survivors to date. Objectives: To assess the test-retest ... -
Telerehabilitation for balance rehabilitation in the subacute stage of stroke: a pilot controlled trial
(NeuroRehabilitation, 2022)BACKGROUND:Telerehabilitation has been proposed as an effective strategy to deliver post-stroke specific exercise. OBJECTIVE:To assess the effectiveness and feasibility of core stability exercises guided ... -
Motor rehabilitation after stroke: European Stroke Organisation (ESO) consensus-based definition and guiding framework
(European Stroke Journal, 2023)Purpose: To propose a consensus-based definition and framework for motor rehabilitation after stroke. Methods: An expert European working group reviewed the literature, attaining internal consensus after ... -
Combined aerobic exercise and high-intensity respiratory muscle training in patients surgically treated for non-small cell lung cancer: a pilot randomized clinical trial
(European Journal of Physical and Rehabilitation Medicine, 2019)BACKGROUND: Lung resection surgery further decreases exercise capacity and negatively affects respiratory muscle function in patients with non-small cell lung cancer (NSCLC). The best design for exercise ... -
Prospective study of shoulder strength, shoulder range of motion, and lymphedema in breast cancer patients from pre-surgery to 5 years after ALND or SLNB
(Supportive Care in Cancer, 2018)Objective: Determine the changes in shoulder strength, shoulder range of motion, and arm volume in breast cancer patients treated with sentinel lymph node biopsy (SLNB) or axillary lymph node dissection ... -
Respiratory muscle strength training and neuromuscular electrical stimulation in subacute dysphagic stroke patients: a randomized controlled trial
(Clinical Rehabilitation, 2016)Objective: To evaluate the effectiveness of inspiratory/expiratory muscle training (IEMT) and neuromuscular electrical stimulation (NMES) to improve dysphagia in stroke. Design: Prospective, single-blind, ... -
Inspiratory and expiratory muscle training in subacute stroke: a randomized clinical trial
(Neurology, 2015)Objective: To assess the effectiveness, feasibility, and safety of short-term inspiratory and expiratory muscle training (IEMT) in subacute stroke patients. Methods: Within 2 weeks of stroke onset, 109 ... -
High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial
(European Journal of Heart Failure, 2014)Aims: The purpose of this study was to evaluate the effectiveness, feasibility, and safety of a 4-week high-intensity inspiratory muscle training (hi-IMT) in patients with chronic heart failure (CHF). ... -
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype
(Nature Metabolism, 2023)Fibrogenesis is part of a normal protective response to tissue injury that can become irreversible and progressive, leading to fatal diseases. Senescent cells are a main driver of fibrotic diseases ... -
Protocol to quantify polyphosphate in human cell lines using a tagged PPBD peptide
(STAR Protocols, 2022)Polyphosphate (polyP) is an evolutionarily conserved polymer of phosphates that is difficult to study in human cells because of its low concentration and high lability. First, we described how to express ... -
CDK-mediated Yku80 phosphorylation regulates the balance between non-homologous end joining (NHEJ) and homologous directed recombination (HDR)
(Journal of Molecular Biology, 2020)There are two major pathways for repairing DNA double-strand breaks (DSBs): homologous directed recombination (HDR) and non-homologous end-joining (NHEJ). While NHEJ functions throughout the cell cycle, ... -
Determination of soluble angiotensin-converting enzyme 2 in saliva samples and its association with nicotine
(Environmental Research, 2023)Introduction: The Angiotensin-Converting Enzyme 2 (ACE2) is the main receptor of the SARS-CoV-2. There is contradictory evidence on how the exposure to nicotine may module the concentration of soluble ...