Ciències de la Salut: Enviaments recents
Ara mostrant els elements 161-180 de 1006
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Impact of Nonsurgical Periodontal Treatment on Blood Pressure: A Prospective Cohort Study
(European Journal of Dentistry, 2024)Objectives: Arterial hypertension and periodontitis are two of the most common diseases worldwide and recent evidence supports a causal relationship between them. Despite all antihypertensive strategies, ... -
Measurement equivalence of PROMIS depression in Spain and the United States
(Psychological Assessment, 2019)In this study, we assessed the psychometric properties of the Spanish Patient-Reported Outcomes Measurement Information System (PROMIS) Depression in an adult population-representative sample from Spain ... -
Change in functioning outcomes as a predictor of the course of depression: a 12-month longitudinal study
(Quality of Life Research, 2018)Purpose: Functioning is a necessary diagnostic criterion for depression, and thus routinely assessed in depressive patients. While it is highly informative of disorder severity, its change has not been ... -
Psychological impact of quarantine on healthcare workers
(Occupational and Environmental Medicine, 2020)Objectives Exposure to infection is an inherent occupational risk for healthcare workers and may lead them to undergo quarantine during disease outbreaks. Both front-line battle and quarantine are ... -
Translational research in psychiatry: The Research Domain Criteria Project (RDoC)
(Revista de Psiquiatría y Salud Mental, 2019)Despite the consensus achieved in the homogenisation of clinical criteria by categorical psychiatric classification systems (DEM and CIE), they are criticised for a lack of validity and inability to ... -
Estimation of the adult population at high risk of developing lung cancer in the European Union
(Cancer Epidemiology, 2018)Background Lung cancer mortality accounts for over 266,000 deaths in the European Union (EU) every year, most of them attributed to smoking. The aim of this study was to estimate the prevalence of the ... -
Relation between tobacco control policies and population at high risk of lung cancer in the European Union
(Environmental Research, 2019)Introduction: Lung cancer accounts for nearly 2 million deaths per year worldwide, the majority of cases due to smoking as the main risk factor associated. The aim of this study was to assess the relation ... -
Precarious employment and health-related outcomes in the European Union: a cross-sectional study
(Critical Public Health, 2019)In this cross-sectional study, we evaluated the associations between precarious employment and health-related outcomes in salaried workers from 28 countries in Europe (2014). We used data from the Flash ... -
Estimación del riesgo de cáncer de pulmón en mujeres que participan en un programa de cribado poblacional de cáncer de mama
(Archivos de Bronconeumología, 2020)Introducción: La mortalidad por cáncer de pulmón está aumentando en mujeres. Se ha proyectado que en España pueda superar a la mortalidad por cáncer de mama, la principal causa de mortalidad por cáncer ... -
Estimation of the population at high risk of developing lung cancer in Chile using simplified eligibility criteria
(Public Health, 2024)Objectives: Several countries in different global regions are implementing lung cancer (LC) screening programmes. This study aimed to estimate the proportion of the Chilean population ≥15 years who are ... -
Dimensional changes of the carpal tunnel and median nerve during manual mobilization of the carpal bones - Anatomical study
(Clinical Biomechanics, 2018)Study design: Cross-sectional study. Background: The carpal tunnel is a clinically important fibro-osseous conduit for the median nerve and associated tendons. It is mechanically dynamic and therapeutic ... -
Control of cell cycle progression by the stress-activated Hog1 MAPK
(Cell Cycle, 2005)Activation of the stress-activated Hog1 kinase is essential for cell survival in response to high osmolarity. The Hog1 SAPK elicits the program for cell adaptation that includes modulation of several ... -
Posttranscriptional control and the role of RNA-binding proteins in gene regulation in trypanosomatid protozoan parasites
(WIREs RNA, 2010)Trypanosomatids are unicellular eukaryotes responsible for severe diseases in humans. They exhibit a number of remarkable biological phenomena, especially at the RNA level. During their life cycles, ... -
Alterations in DRBD3 Ribonucleoprotein Complexes in Response to Stress in Trypanosoma brucei
(PLOS One, 2012)Regulation of RNA polymerase II transcription initiation is apparently absent in trypanosomes. Instead, these eukaryotes control gene expression mainly at the post-transcriptional level. Regulation is ... -
A short RNA stem–loop is necessary and sufficient for repression of gene expression during early logarithmic phase in trypanosomes
(Nucleic Acids Research, 2014)We have compared the transcriptomes of cultured procyclic Trypanosoma brucei cells in early and late logarithmic phases and found that ∼200 mRNAs were differentially regulated. In late log phase cells, ... -
Depletion of the RNA-binding protein RBP33 results in increased expression of silenced RNA polymerase II transcripts in trypanosoma brucei
(PLOS One, 2014)We have characterized the RNA-binding protein RBP33 in Trypanosoma brucei, and found that it localizes to the nucleus and is essential for viability. The subset of RNAs bound to RBP33 was determined by ... -
Meet the players: local translation at the synapse
(Frontiers in Molecular Neuroscience, 2014)It is widely believed that activity-dependent synaptic plasticity is the basis for learning and memory. Both processes are dependent on new protein synthesis at the synapse. Here, we describe a mechanism ... -
CLIPing Staufen to secondary RNAstructures: Size and location matter!
(BioEssays, 2015)hiCLIP (RNA hybrid and individual-nucleotide resolution ultraviolet cross-linking and immunoprecipitation), is a novel technique developed by Sugimoto et al. (2015). Here, the use of different adaptors ... -
RNA transport: from head to toe in radial glial cells
(Current Biology, 2016)Intracellular mRNA localization critically contributes to proper brain development and function. A recent study demonstrates that mRNAs are actively transported in radial glial cells from the soma to ... -
A retained intron in the 3′‐UTR of Calm3 mRNA mediates its Staufen2‐ and activity‐dependent localization to neuronal dendrites
(EMBO Reports, 2017)Dendritic localization and hence local mRNA translation contributes to synaptic plasticity in neurons. Staufen2 (Stau2) is a well‐known neuronal double‐stranded RNA‐binding protein (dsRBP) that has been ...