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Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway
(Springer Nature, 2021)
Purpose: Cancer stem cells represent a cancer cell subpopulation that has been found to be associated with metastasis and chemoresistance. Therefore, it is vital to identify mechanisms regulating cancer ...
Functional genomics approaches to elucidate vulnerabilities of intrinsic and acquired chemotherapy resistance
(MDPI, 2021)
Drug resistance is a commonly unavoidable consequence of cancer treatment that results in therapy failure and disease relapse. Intrinsic (pre-existing) or acquired resistance mechanisms can be drug-specific ...