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Susceptibility to severe acute respiratory syndrome coronavirus 2 infection among children and adults: a seroprevalence study of family households in the Barcelona metropolitan region, Spain
(Oxford University Press, 2021-06)
Background: Susceptibility of children and adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and persistence of antibody response to the virus after infection resolution ...
Exploring the nasopharyngeal microbiota composition in infants with whooping cough: a test-negative case-control study
(Public Library of Science, 2021)
Purpose: The purpose of this study was to characterize the nasopharyngeal microbiota of infants with possible and confirmed pertussis compared to healthy controls. Methods: This prospective study included ...
Rapid increase of oral bacteria in nasopharyngeal microbiota after antibiotic treatment in children with invasive pneumococcal disease
(Frontiers Media, 2021)
Introduction: Antibiotics are commonly prescribed to young children for treating bacterial infections such as invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae. Despite the obvious ...
Rapid molecular syndromic testing for aetiological diagnosis of gastrointestinal infections and targeted antimicrobial prescription: experience from a reference paediatric hospital in Spain
(Springer Nature, 2021)
Aetiological diagnosis of gastrointestinal infections is challenging since a wide range of bacteria, parasites and viruses can be causal agents and derived clinical manifestations appear quite similar. ...
Validation and implementation of a direct RT-qPCR method for rapid screening of SARS-CoV-2 infection by using non-invasive saliva samples
(Elsevier, 2021)
Objective: To validate and implement an optimized screening method for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA combining use of self-collected raw saliva samples, ...
Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases
(Springer Nature, 2020)
The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ...
Impact of COVID-19 lockdown on the nasopharyngeal microbiota of children and adults self-confined at home
(MDPI, 2022)
The increased incidence of COVID-19 cases and deaths in Spain in March 2020 led to the declaration by the Spanish government of a state of emergency imposing strict confinement measures on the population. ...
The positive rhinovirus/enterovirus detection and SARS-CoV-2 persistence beyond the acute infection phase: an intra-household surveillance study
(MDPI, 2021)
We aimed to assess the duration of nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA persistence in adults self-confined at home after acute infection; and to identify the ...
Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis
(Wolters Kluwer, 2020)
Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ...
Low transmission of SARS-CoV-2 derived from children in family clusters: an observational study of family households in the Barcelona Metropolitan Area, Spain
(Public Library of Science, 2022)
Background: Family clusters offer a good opportunity to study viral transmission in a stable setting. We aimed to analyze the specific role of children in transmission of SARS-CoV-2 within households. ...