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Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
(Cold Spring Harbor Laboratory Press, 2014)
The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ...
Hymenal tags of the newborn
(ACT Publishing Group Limited, 2019)
Evaluation of female newborn genitalia should always be carried out at pre-discharge visit in hospital nurseries in order to exclude gross malformations, potentially compatible with genetic and/or ...
Pneumococcal serotypes in children, clinical presentation and antimicrobial susceptibility in the PCV13 era
(Cambridge University Press, 2020-11)
The aim was to analyse invasive pneumococcal disease (IPD) serotypes in children aged ⩽17 years according to clinical presentation and antimicrobial susceptibility. We conducted a prospective study ...
Ozenoxacin, a new effective and safe topical treatment for impetigo in children and adolescents
(Karger, 2020)
Background: Ozenoxacin is a topical antibiotic approved in Europe to treat non-bullous impetigo in adults and children aged ≥6 months. This analysis evaluated the efficacy and safety of ozenoxacin in ...
An effect of bilingualism on the auditory cortex
(Society for Neuroscience, 2012-11)
Two studies (Golestani et al., 2007; Wong et al., 2008) have reported a positive correlation between the ability to perceive foreign speech sounds and the volume of Heschl's gyrus (HG), the structure ...
Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016
(European Centre for Disease Prevention and Control (ECDC), 2019-02)
Enterovirus 71 (EV-A71) is a small, non-enveloped, single-stranded RNA virus that belongs to the species Enterovirus A along with 24 other serotypes within the Enterovirus genus [1]. According to the ...
Covid-19, an opportunity to compare in-person and online teaching
(Centro de Estudios en Educación Médica, 2021)
For years it has been discussed the dichotomy between traditional in-person teaching versus online instruction. The lockdown, consequence of the Covid-19 pandemic, gave us an opportunity to gain evidence ...
Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome
(Frontiers Media, 2021-04)
Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main ...
A two-point ultrasound-guided injection technique for the transversus thoracis plane block: a canine cadaveric study
(MDPI, 2022)
The transversus thoracis plane block is a locoregional technique recently described in canine cadavers to desensitize the intercostal nerves running through this plane. In canine cadavers, a transverse ...
CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
(Elsevier, 2019-01)
Objective: Carnitine palmitoyltransferase 1C (CPT1C) is implicated in central regulation of energy homeostasis. Our aim was to investigate whether CPT1C in the ventromedial nucleus of the hypothalamus ...