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Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
(Molecular Neurobiology, 2018)
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...
Determining the value of two biologic drugs for chronic inflammatory skin diseases: results of a multi-criteria decision analysis
(Springer Nature, 2018)
Background and Objective: Multi-criteria decision analysis (MCDA) is a tool that systematically considers multiple factors relevant to health decision-making. The aim of this study was to use an MCDA ...
Impacto de la crisis económica en la actividad y eficiencia de un hospital terciario universitario
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Fundamentos: La crisis económica iniciada el año 2008 provocó una caída importante del gasto sanitario público en España. El objetivo del estudio fue evaluar el impacto de la crisis en la actividad, ...
Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
(Public Library of Science, 2018-08-06)
Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms
remain unknown. Using various orthogonal single-cell approaches, we show that cell size
increases linearly ...
Mobility Difficulties, Physical Activity, and All-cause Mortality Risk in a Nationally representative Sample of Older Adults
(Gerontological Society of America by Oxford University Press, 2018)
This study sought to determine the association between levels of physical activity and mobility difficulties and time to death while accounting for the effect of several confounders. We also examined ...
ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer
(Impact Journals, 2018-03-30)
Endometrial cancer (EC) is the sixth deadliest cancer in women. The depth of myometrial invasion is one of the most important prognostic factors, being directly associated with tumor recurrence and ...
Prospective study of shoulder strength, shoulder range of motion, and lymphedema in breast cancer patients from pre-surgery to 5 years after ALND or SLNB
(Springer Nature, 2018)
Objective: Determine the changes in shoulder strength, shoulder range of motion, and arm volume in breast cancer patients treated with sentinel lymph node biopsy (SLNB) or axillary lymph node dissection ...
Basic life support and external defibrillation competences after instruction and at 6 months comparing face-to-face and blended training. Randomised trial
(Elsevier, 2018)
Aim of the Study: The objective of this study was to compare the immediate and 6-month efficacy of basic life support (BLS) and automatic external defibrillation (AED) training using standard or blended ...
Multiorgan dysfunction in infants of 33-35 weeks gestation with severe hypoxic-ischemic encephalopathy treated with hypothermia anatomy & physiology
(Longdom Publishing, 2018)
Background: The benefits of hypothermia on neurodevelopment of newborns ≥ 36 weeks gestation with hypoxicischemic encephalopathy have been shown in large clinical trials. The security of hypothermia in ...
High red blood cell distribution width as a marker of hospital mortality after ICU discharge: a cohort study
(Springer Nature, 2018-11-16)
Background: High red blood cell distribution width (RDW) is associated with worse outcome in diverse scenarios, including in critical illness. The Sabadell score (SS) predicts in-hospital survival after ...