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Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts
(Public Library of Science, 2019)
Pulmonary fibrosis (PF) is the result of chronic injury where fibroblasts become activated and secrete large amounts of extracellular matrix (ECM), leading to impaired fibroblasts degradation followed ...
Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona, Spain
(Wolters Kluwer, 2017-07)
Cohort studies of large series of patients with sarcoidosis over a long period of time are scarce. The aim of this study is to report a 40-year clinical experience of a large series of patients at ...
CoDysAn: a telemedicine tool to improve awareness and diagnosis for patients with congenital dyserythropoietic anemia
(Frontiers Media, 2019)
Congenital Dyserythropoietic Anemia (CDA) is a heterogeneous group of hematological disorders characterized by chronic hyporegenerative anemia and distinct morphological abnormalities of erythroid ...
Standardizing admission and discharge processes to improve patient flow: a cross sectional study
(Springer Nature, 2012-06-28)
Background: The aim of this study was to evaluate how hospital capacity was managed focusing on standardizing the admission and discharge processes. Methods: This study was set in a 900-bed university ...
Visual outcome and complications of cataract extraction after pars plana vitrectomy
(Dove Press, 2018)
Purpose: To evaluate the visual outcomes and complications of phacoemulsification in previously vitrectomized eyes. Patients and methods: A retrospective analysis of 87 consecutive vitrectomized eyes ...
Increased infammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice
(Springer Nature, 2017-11-22)
Obesity is associated with severe metabolic diseases such as type 2 diabetes, insulin resistance, cardiovascular disease and some forms of cancer. The pathophysiology of obesity-induced metabolic diseases ...
Impacto de la violencia colectiva en la salud. Resultados del estudio ISAVIC en el País Vasco
(Elsevier, 2011)
Objetivo: A pesar de la ubicuidad de la violencia y de su posible importancia para la salud de las personas y las colectividades, su papel y mecanismos de acción en este sentido no están apenas analizados. ...
Aprendizaje de las competencias de investigación en el Grado de Medicina: análisis y evaluación de las calificaciones de los estudiantes en el Trabajo de Final de Grado
(Universidad de Murcia, 2016)
La adaptación al Plan Bolonia del Grado de Medicina en España ha introducido en los planes de estudio la realización del Trabajo de Final de Grado (TFG). A continuación se presenta un modelo de TFG y ...
Determining the value of two biologic drugs for chronic inflammatory skin diseases: results of a multi-criteria decision analysis
(Springer Nature, 2018)
Background and Objective: Multi-criteria decision analysis (MCDA) is a tool that systematically considers multiple factors relevant to health decision-making. The aim of this study was to use an MCDA ...
Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
(Springer Nature, 2019-07-05)
Background: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be ...