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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
(Springer Nature, 2018)
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...
Evaluation of the retinal nerve fiber layer Thickness, the mean deviation, and the visual field index in progressive glaucoma
(Wolters Kluwer Health, 2016)
PURPOSE: To determine and compare the retinal nerve fiber layer (RNFL) thickness, the mean deviation, and the visual field index (VFI) in glaucoma cases with progression detected by spectral domain ...
Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort
(Elsevier, 2017-06)
Background: The leading high-risk state for diabetes mellitus (DM) – prediabetes – is increasing; however, a lack of information exists in oldest old subjects. The objective of this study is to describe ...
Plataformas digitales y empleo: necesidad de monitorización y vigilancia de Salud Pública
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Actualmente, la relación entre las condiciones del trabajo y empleo con la salud es bien conocida, además esta relación es un importante determinante social de la salud de la población trabajadora ...
Esperanza de vida entre 1991-2011: explicación epidemiológica a la desigualdad por género en Tarragona, una provincia de Cataluña, España
(Centro Centroamericano de Población; Universidad de Costa Rica, 2013)
El objetivo de esta investigación es determinar si las distintas causas de muerte explicarían la desigualdad de la mortalidad por sexo entre 1991 y 2011 en la provincia de Tarragona (Cataluña, España) ...
Internalizing and externalizing symptoms and suicidal behaviour in young people: a systematic review and meta-analysis of longitudinal studies
(Wiley-Blackwell, 2019-07)
Objective: To assess internalizing and externalizing symptoms as risk factors for suicidal behaviour and suicide among adolescents and young adults. Method: We conducted a systematic review of articles ...
Mechanisms of CPT1C-Dependent AMPAR trafficking enhancement
(Frontiers Media, 2018-08-08)
In neurons, AMPA receptor (AMPAR) function depends essentially on their constituent
components: the ion channel forming subunits and ion channel associated proteins.
On the other hand, AMPAR trafficking ...
Biofunctionalization with a TGFβ-1 inhibitor peptide in the osseointegration of synthetic bone grafts: an in vivo study in beagle dogs
(MDPI, 2019-09-27)
Objectives: The aim of this research was to determine the osseointegration of two presentations of biphasic calcium phosphate (BCP) biomaterial—one untreated and another submitted to biofunctionalization ...
Task-dependent modulation of the visual sensory thalamus assists visual-speech recognition
(Elsevier, 2018-09)
The cerebral cortex modulates early sensory processing via feed-back connections to sensory pathway nuclei. The functions of this top-down modulation for human behavior are poorly understood. Here, we ...
Prevention of posterior capsule opacification through intracapsular hydrogen peroxide or distilled water treatment in human donor tissue
(Springer Nature, 2018)
In order to determine whether posterior capsule opacification after cataract surgery, could be delayed or inhibited through the application of hydrogen peroxide (H2O2) or distilled water (H2Od),we ...