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Unilateral hypertrophy of the inner lip
(Maples Scientific Publishers, 2019-09-30)
Variations on normality on the vulvar aspect have generated many difficulties among general pediatricians.The great amount of aesthetical perfection has led to an increasing number of adolescents seeking ...
Hydrops fetalis caused by congenital syphilis: an ancient disease?
(Sage Journals, 2019)
Syphilis is currently an emerging health problem, especially in high-income countries. Infection rates have increased significantly in European countries such as the United Kingdom and Spain in the last ...
Inspiratory and expiratory muscle training in subacute stroke: a randomized clinical trial
(American Academy of Neurology, 2015)
Objective: To assess the effectiveness, feasibility, and safety of short-term inspiratory and expiratory muscle training (IEMT) in subacute stroke patients. Methods: Within 2 weeks of stroke onset, 109 ...
Determining the value of two biologic drugs for chronic inflammatory skin diseases: results of a multi-criteria decision analysis
(Springer Nature, 2018)
Background and Objective: Multi-criteria decision analysis (MCDA) is a tool that systematically considers multiple factors relevant to health decision-making. The aim of this study was to use an MCDA ...
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance
(Elsevier, 2014-10)
Hypothalamic endoplasmic reticulum (ER) stress is a key mechanism leading to obesity. Here, we demonstrate that ceramides induce lipotoxicity and hypothalamic ER stress, leading to sympathetic inhibition, ...
Impacto de la crisis económica en la actividad y eficiencia de un hospital terciario universitario
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Fundamentos: La crisis económica iniciada el año 2008 provocó una caída importante del gasto sanitario público en España. El objetivo del estudio fue evaluar el impacto de la crisis en la actividad, ...
Nasopharyngeal microbiota in children with invasive pneumococcal disease: identification of bacteria with potential disease-promoting and protective effects
(Frontiers Media, 2019)
Background and Aims: The risk of suffering from some infectious diseases can be related to specific microbiota profiles. Specifically, the nasopharyngeal microbiota could play a role as a risk or ...
Nucleosome architecture throughout the cell cycle
(Nature Research, 2016-01-28)
Nucleosomes provide additional regulatory mechanisms to transcription and DNA replication
by mediating the access of proteins to DNA. During the cell cycle chromatin undergoes several
conformational ...
Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
(Public Library of Science, 2018-08-06)
Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms
remain unknown. Using various orthogonal single-cell approaches, we show that cell size
increases linearly ...
Exploring the link between MORF4L1 and risk of breast cancer
(Springer Nature, 2011)
Introduction: Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling pathway. To gain deeper insight into this pathway ...