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Evaluation of the immunomodulatory effects of cobalt, copper and magnesium ions in a pro inflammatory environment
(Springer Nature, 2021)
Biomaterials and scaffolds for Tissue Engineering are widely used for an effective healing and regeneration. However, the implantation of these scaffolds causes an innate immune response in which the ...
Factors associated with depression and anxiety in adults ≥60 years old during the COVID-19 pandemic: a systematic review
(MDPI, 2021)
COVID-19 represents a threat to public health and the mental health of the aged population. Prevalence and risk factors of depression and anxiety have been reported in previous reviews in other populations; ...
Correlation between tobacco control policies and mortality of haematological cancers across Europe: an ecological study
(European Publishing, 2021)
Introduction: To determine the correlation between tobacco control policies and mortality of haematological malignancies: leukemia, lymphoma and multiple myeloma (MM). Methods: Ecological study with the ...
Genetic screening for TLR7 variants in young and previously healthy men with severe COVID-19
(Frontiers Media S.A., 2021)
Introduction: Loss-of-function TLR7 variants have been recently reported in a small number of males to underlie strong predisposition to severe COVID-19. We aimed to determine the presence of these rare ...
Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
(Springer Nature, 2021)
The ideal moment to withdraw respiratory supply of patients under Mechanical Ventilation at Intensive Care Units (ICU), is not easy to be determined for clinicians. Although the Spontaneous Breathing ...
The return of malonyl-CoA to the brain: cognition and other stories
(Elsevier, 2021-01)
Nutrients, hormones and the energy sensor AMP-activated protein kinase (AMPK) tightly regulate the intracel-lular levels of the metabolic intermediary malonyl-CoA, which is a precursor of fatty ...
The dermoscopic “chromosome arms sign” for terra firma-forme dermatosis
(Openventio Publishers, 2021)
Introduction: Terra firma-forme dermatosis (TFFD) belongs to the group of “dirty dermatoses” and represents a not well-known and surely underestimated skin condition. Clinical cases: We present 2 cases ...
Functional genomics approaches to elucidate vulnerabilities of intrinsic and acquired chemotherapy resistance
(MDPI, 2021)
Drug resistance is a commonly unavoidable consequence of cancer treatment that results in therapy failure and disease relapse. Intrinsic (pre-existing) or acquired resistance mechanisms can be drug-specific ...
Catheter-directed therapies in patients with pulmonary embolism: predictive factors of in-hospital mortality and long-term follow-up
(MDPI, 2021)
Background: Catheter-directed therapies (CDT) may be considered for selected patients with pulmonary embolism (PE); (2) Methods: Retrospective observational study including all consecutive patients with ...