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Development of a serum-free medium to aid large-scale production of mycoplasma-based therapies
(American Society for Microbiology, 2023)
To assist in the advancement of the large-scale production of safe Mycoplasma vaccines and other Mycoplasma-based therapies, we developed a culture medium free of animal serum and other animal components ...
Predicting the onset of diabetes-related complications after a diabetes diagnosis with machine learning algorithms
(Elsevier, 2023)
Aims: Using machine learning algorithms and administrative data, we aimed to predict the risk of being diagnosed with several diabetes-related complications after one-, two- and three-year post-diabetes ...
Reducing the duration of antibiotic therapy in surgical patients through a specific nationwide antimicrobial stewardship program. A prospective, interventional cohort study
(Elsevier, 2023)
Background: Guidelines recommend 5–7 days of antibiotic treatment in patients with surgical infection and adequate source control. This nationwide stewardship intervention aimed to reduce the duration ...
How has the strict lockdown during the SARS-COV-2 outbreak changed the diet of Spaniards?
(Elsevier, 2023)
Purpose: We investigate the impact of a specific macroeconomic shock that occurred as a response to the SARS-COV-2 outbreak, namely the strict lockdown imposed in Spain on the March 14, 2020. Methods: ...
Statins in cancer prevention and therapy
(MDPI, 2023)
Statins, a class of HMG-CoA reductase inhibitors best known for their cholesterol-reducing and cardiovascular protective activity, have also demonstrated promise in cancer prevention and treatment. This ...
Early management of severe biliary infection in the era of the Tokyo guidelines
(MDPI, 2023)
Sepsis of biliary origin is increasing worldwide and has become one of the leading causes of emergency department admissions. The presence of multi-resistant bacteria (MRB) is increasing, and mortality ...
Precision and safety of ultrasound-guided versus palpation-guided needle placement on the patellar tendon: a cadaveric study
(MDPI, 2023)
For decades, needling interventions have been performed based on manual palpation and anatomic knowledge. The increasing use of real-time ultrasonography in clinical practice has improved the accuracy ...
Biomedical doctoral students’ research practices when facing dilemmas: two vignette-based randomized control trials
(Springer Nature, 2023)
Our aim was to describe the research practices of doctoral students facing a dilemma to research integrity and to assess the impact of inappropriate research environments, i.e. exposure to (a) a ...
CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non-associative learning
(Wiley, 2023)
Carnitine palmitoyltransferase 1c (CPT1C) is a neuron-specific protein widely distributed throughout the CNS and highly expressed in discrete brain areas including the hypothalamus, hippocampus, amygdala ...
Development of a Guide to Multidimensional Needs Assessment in the Palliative Care Initial Encounter (MAP)
(Elsevier, 2023-10)
Context: Ensuring patient-centered palliative care requires a comprehensive assessment of needs beginning in the initial encounter. However, there is no generally accepted guide for carrying out this ...