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Computational modeling as a tool to investigate PPI: from drug design to tissue engineering
(Frontiers Media S.A., 2021)
Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the ...
Diagnostic performance of the physical activity-related question of the GINA questionnaire to detect exercise-induced bronchoconstriction in asthma
(Elsevier, 2021-07)
Introduction: The aim of the study was to evaluate the diagnostic performance of the item concerning physical activity of the Global Initiative for Asthma (GINA) asthma control questionnaire for detection ...
Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study
(Elsevier, 2020-08)
Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ...
Effects of a short-term resistance-training program on heart rate variability in children with cystic fibrosis: a randomized controlled trial
(Frontiers Media, 2021)
Background: Cystic fibrosis (CF) affects the autonomic nervous system (ANS) and exercise in healthy children modulates the interaction between sympathetic and parasympathetic activity. This study aimed ...
Physicochemical properties of lipoproteins assessed by nuclear magnetic resonance as a predictor of premature cardiovascular disease. PRESARV-SEA study
(MDPI, 2021)
Some lipoprotein disorders related to the residual risk of premature cardiovascular disease (PCVD) are not detected by the conventional lipid profile. In this case-control study, the predictive power ...
Proteasomal-mediated degradation of AKAP150 accompanies AMPAR endocytosis during cLTD
(Society for Neuroscience, 2020-03-23)
The number and function of synaptic AMPA receptors (AMPARs) tightly regulates excitatory synaptic transmission. Current evidence suggests that AMPARs are inserted into the postsynaptic membrane during ...
Validation of an online version of the alcohol use disorders identification test (AUDIT) for alcohol screening in spanish university students
(MDPI, 2021)
Online alcohol screening may be helpful in preventing alcohol use disorders. We assessed psychometric properties of an online version of the Alcohol Use Disorders Identification Test (AUDIT) among Spanish ...
Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
(Springer Nature, 2021)
The ideal moment to withdraw respiratory supply of patients under Mechanical Ventilation at Intensive Care Units (ICU), is not easy to be determined for clinicians. Although the Spontaneous Breathing ...
The positive rhinovirus/enterovirus detection and SARS-CoV-2 persistence beyond the acute infection phase: an intra-household surveillance study
(MDPI, 2021)
We aimed to assess the duration of nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA persistence in adults self-confined at home after acute infection; and to identify the ...
Manejo de pacientes en cirugía oral y maxilofacial durante el periodo de crisis y de control posterior de la pandemia de COVID-19
(Inspira Network, 2020)
La pandemia por la nueva infección respiratoria conocida como enfermedad coronavirus 2019 (COVID-19), causada por el virus SARS-CoV-2, ha desencadenado una perturbación sin precedentes en la actividad ...