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Blood test dynamics in hospitalized COVID-19 patients: Potential utility of D-dimer for pulmonary embolism diagnosis
(Public Library of Science, 2020-12-28)
Background: A higher incidence of thrombotic events, mainly pulmonary embolism (PE), has been reported in hospitalized patients with COVID-19. The main objective was to assess clinical and laboratory ...
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
(Springer Nature, 2010)
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations ...
Beneficial effect of corticosteroids in preventing mortality in patients receiving tocilizumab to treat severe COVID-19 illness
(International Journal of Infectious Diseases, 2020-12)
Objectives: To assess the characteristics and risk factors for mortality in patients with severe coronavirus disease-2019 (COVID-19) treated with tocilizumab (TCZ), alone or in combination with ...
Nucleosome architecture throughout the cell cycle
(Nature Research, 2016-01-28)
Nucleosomes provide additional regulatory mechanisms to transcription and DNA replication
by mediating the access of proteins to DNA. During the cell cycle chromatin undergoes several
conformational ...
Manejo de pacientes en cirugía oral y maxilofacial durante el periodo de crisis y de control posterior de la pandemia de COVID-19
(Inspira Network, 2020)
La pandemia por la nueva infección respiratoria conocida como enfermedad coronavirus 2019 (COVID-19), causada por el virus SARS-CoV-2, ha desencadenado una perturbación sin precedentes en la actividad ...
Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
(Public Library of Science, 2018-08-06)
Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms
remain unknown. Using various orthogonal single-cell approaches, we show that cell size
increases linearly ...
Exploring the link between MORF4L1 and risk of breast cancer
(Springer Nature, 2011)
Introduction: Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling pathway. To gain deeper insight into this pathway ...
Contact dermatitis in children: a 16-year study of 396 children
(Yumed Text Publications, 2019-08)
Background: Contact dermatitis in continuing to be increasingly recognized in pediatric populations, especially in those with atopic dispositions. Exposures in children parallel those seen in adult ...
Histological comparison of in vitro and in vivo development of peripheral posterior capsule opacification in human donor tissue
(Elsevier, 2019)
In order to study the mechanisms involved in the development of posterior capsule opacification (PCO) we compared in vivo developed PCO with PCO formed in tissue culture with focus on the periphery of ...