Browsing Ciències de la Salut by Subject "Receptor de progesterona"
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90 years of progesterone: molecular mechanisms of progesterone receptor action on the breast cancer genome
(Journal of Molecular Endocrinology, 2020)Gene regulation by steroid hormones has been at the forefront in elucidating the intricacies of transcriptional regulation in eukaryotes ever since the discovery by Karlson and Clever that the insect ... -
Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
(Genes & Development, 2014)The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ...