Now showing items 1-2 of 2

    • CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst 

      Zagmutt, Sebastián; Mera, Paula; González García, Ismael; Ibeas, Kevin; Romero, María del Mar; Obri, Arnaud; Martin, Beatriz; Esteve Codina, Anna; Soler Vázquez, M. Carmen; Bastias Pérez, Marianela; Cañes, Laia; Augé, Elisabeth; Pelegri, Carme; Vilaplana, Jordi; Ariza, Xavier; García, Jordi; Martinez González, José; Casals, Núria; López, Miguel; Palmiter, Richard; Sanz, Elisenda; Quintana, Albert; Herrero, Laura; Serra, Dolors (Biology of Sex Differences, 2023)
      Background: Fatty acid metabolism in the hypothalamus has an important role in food intake, but its specific role in AgRP neurons is poorly understood. Here, we examined whether carnitinea palmitoyltransferase ...
    • Implantation of CPT1AM-expressing adipocytes reduces obesity and glucose intolerance in mice 

      Soler Vázquez, M. Carmen; Romero, María del Mar; Todorcevic, Marijana; Delgado, Katia; Calatayud, Carles; Benitez Amaro, Aleyda; La Chica Lhoëst, Maria Teresa; Mera, Paula; Zagmutt, Sebastián; Bastías Pérez, Marianela; Ibeas, Kevin; Casals, Núria; Escolà Gil, Joan Carles; Llorente Cortés, Vicenta; Consiglio, Antonella; Serra, Dolors; Herrero, Laura (Metabolic Engineering, 2023-05)
      Obesity and its associated metabolic comorbidities are a rising global health and social issue, with novel therapeutic approaches urgently needed. Adipose tissue plays a key role in the regulation of ...