Browsing Ciències de la Salut by Title
Now showing items 89-108 of 736
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Bullous henoch-schönlein purpura: a case series
(Journal of Respiratory Research, 2019-12)Henoch-Schönlein purpura (HSP) represents the most common vasculitis in children. Typically, HSP manifests with palpable purpura and edema, usually following an urticarial or erythematous maculopapular ... -
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Preventive Medicine, 2019-12)Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ... -
Caracterización del microbioma nasofaríngeo en pacientes con enfermedad de Kawasaki
(2022)Introducción: La etiología de la enfermedad de Kawasaki (EK) sigue siendo desconocida. Varios estudios han relacionado el microbioma humano con algunas enfermedades. Sin embargo, los estudios sobre el ... -
Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
(Scientific Reports, 2021)The ideal moment to withdraw respiratory supply of patients under Mechanical Ventilation at Intensive Care Units (ICU), is not easy to be determined for clinicians. Although the Spontaneous Breathing ... -
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
(British Journal of Pharmacology, 2021-01)Background and Purpose: The enzyme α/β‐hydrolase domain containing 6 (ABHD6), a new member of the endocannabinoid system, is a promising therapeutic target against neuronal‐related diseases. However, ... -
Catheter-directed therapies in patients with pulmonary embolism: predictive factors of in-hospital mortality and long-term follow-up
(Journal of Clinical Medicine, 2021)Background: Catheter-directed therapies (CDT) may be considered for selected patients with pulmonary embolism (PE); (2) Methods: Retrospective observational study including all consecutive patients with ... -
CDK-mediated Yku80 phosphorylation regulates the balance between non-homologous end joining (NHEJ) and homologous directed recombination (HDR)
(Journal of Molecular Biology, 2020)There are two major pathways for repairing DNA double-strand breaks (DSBs): homologous directed recombination (HDR) and non-homologous end-joining (NHEJ). While NHEJ functions throughout the cell cycle, ... -
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
(Molecular Oncology, 2023)Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ... -
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
(Molecular Oncology, 2023)Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ... -
Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy
(npj Breast Cancer, 2024)In this study, we performed genomic analyses of cell cycle and tumor microenvironment changes during and after ribociclib and letrozole or chemotherapy in the CORALLEEN trial. 106 women with untreated ... -
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance
(Cell Reports, 2014-10)Hypothalamic endoplasmic reticulum (ER) stress is a key mechanism leading to obesity. Here, we demonstrate that ceramides induce lipotoxicity and hypothalamic ER stress, leading to sympathetic inhibition, ... -
Central regulation of brown fat thermogenesis in response to saturated or unsaturated long-chain fatty acids
(International Journal of Molecular Sciences, 2023)Sensing of long-chain fatty acids (LCFA) in the hypothalamus modulates energy balance, and its disruption leads to obesity. To date, the effects of saturated or unsaturated LCFA on hypothalamic-brown ... -
Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
(PLoS Biology, 2018-08-06)Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms remain unknown. Using various orthogonal single-cell approaches, we show that cell size increases linearly ... -
Cerebral oximetry monitoring in extremely preterm infants
(The New England Journal of Medicine, 2023)BACKGROUND: The use of cerebral oximetry monitoring in the care of extremely preterm infants is increasing. However, evidence that its use improves clinical outcomes is lacking.: METHODS: In this ... -
Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases
(Scientific Reports, 2020)The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ... -
Cervical manipulation versus thoracic or cervicothoracic manipulations for the management of neck pain. A systematic review and meta-analysis
(Musculoskeletal Science and Practice, 2024)Background: Cervical and thoracic thrust or non-thrust manipulations have shown to be effective in patients with neck pain, but there is a lack of studies comparing both interventions in patients with ... -
Challenges for hospital management in supporting nurses to deliver humanized care
(Nursing Inquiry, 2021)Hospitals are paying increasing attention to the delivery of humanized care. The purpose of this study was to explore from the nursing perspective what hospital managers might do to facilitate this. A ... -
Challenges in using both eyes of the same patient when evaluating the results after implantation of intrastromal corneal ring segments
(Acta Ophthalmologica, 2020)Purpose: To assess correlation between results from both eyes of the same patient after implantation of intrastromal corneal ring segments (ICRS) and define whether they can be used together in clinical ... -
Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project
(Microorganisms, 2021)Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. ... -
Changes in invasive pneumococcal disease in the paediatric population in the second COVID-19 pandemic year
(Vaccines, 2023)Incidence of invasive pneumococcal disease (IPD) decreased worldwide in 2020, coinciding with the implementation of measures to reduce COVID-19 transmission. We evaluated the impact of the COVID-19 ...