Browsing Ciències de la Salut by Title
Now showing items 485-504 of 736
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Novel mutations in the ferritin-L iron-responsive element that only mildly impair IRP binding cause hereditary hyperferritinaemia cataract syndrome
(Orphanet Journal of Rare Diseases, 2013)Background: Hereditary Hyperferritinaemia Cataract Syndrome (HHCS) is a rare autosomal dominant disease characterized by increased serum ferritin levels and early onset of bilateral cataract. The disease ... -
Novel nanostructured lipid carriers loading Apigenin for anterior segment ocular pathologies
(International Journal of Pharmaceutics, 2024)Dry eye disease (DED) is a chronic multifactorial disorder of the ocular surface caused by tear film dysfunction and constitutes one of the most common ocular conditions worldwide. However, its treatment ... -
Novel regulation of the synthesis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunit gluA1 by carnitine palmitoyltransferase 1C (CPT1C) in the hippocampus
(Journal of Biological Chemistry, 2015-10-16)The regulation of AMPA-type receptor (AMPAR) abundance in the postsynaptic membrane is an important mechanism involved in learning and memory formation. Recent data suggest that one of the constituents ... -
Nucleosome architecture throughout the cell cycle
(Scientific Reports, 2016-01-28)Nucleosomes provide additional regulatory mechanisms to transcription and DNA replication by mediating the access of proteins to DNA. During the cell cycle chromatin undergoes several conformational ... -
Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival
(Journal of Biological Chemistry, 2012-03-30)NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ... -
Occupational aspects of emergency medicine practice in Catalonia: the OPENCAT opinion survey
(Emergencias, 2017)Objectives: To gather information on the contracting and training of members of the Catalan Society of Emergency Medicine (SoCMUE) who work in emergency medicine and services in Catalonia. To survey ... -
Oozing: an accessible technique to create 3D-printed scaffolds suitable for tissue engineering
(International Journal of Bioprinting, 2024)Tissue-engineered constructs require mimicking the extracellular matrix microenvironment of native tissue for better promoting cell growth. Commercial three-dimensional (3D) printers provide a versatile ... -
Opinión de los responsables de los servicios de urgencias hospitalarios de Cataluña acerca de la creación de la especialidad de Medicina de Urgencias y Emergencias
(Emergencias, 2015)Objetivo. Conocer la opinión de los responsables de los servicios de urgencias hospitalarios (SUH) de Cataluña respecto al soporte e impacto que tendría la creación de la especialidad primaria de Medicina ... -
Optimized metrics for orthogonal combinatorial CRISPR screens
(Scientific Reports, 2023)CRISPR-based gene perturbation enables unbiased investigations of single and combinatorial genotype-to-phenotype associations. In light of efforts to map combinatorial gene dependencies at scale, choosing ... -
Oral antibiotic prophylaxis lowers surgical site infection in elective colorectal surgery: results of a pragmatic cohort study in Catalonia
(Journal of Clinical Medicine, 2021)Background: The role of oral antibiotic prophylaxis (OAP) and mechanical bowel preparation (MBP) in the prevention of surgical site infection (SSI) after colorectal surgery is still controversial. The ... -
Oscillation encoding of individual differences in speech perception
(PLoS One, 2014-07-03)Individual differences in second language (L2) phoneme perception (within the normal population) have been related to speech perception abilities, also observed in the native language, in studies assessing ... -
Osseointegration of sandblasted and acid-etched implant surfaces. A histological and histomorphometric study in the rabbit
(International Journal of Molecular Sciences, 2021)Titanium surface is an important factor in achieving osseointegration during the early wound healing of dental implants in alveolar bone. The purpose of this study was to evaluate sandblasted-etched ... -
Osteo-odonto-, tibial bone and Boston keratoprosthesis in clinically comparable cases of chemical injury and autoimmune disease
(The Ocular Surface, 2019)Purpose: To compare anatomical and functional results between three types of keratoprosthesis (KPro) in chemical injury and autoimmune disease. Methods: 70 clinically comparable cases were included as ... -
Ozenoxacin, a new effective and safe topical treatment for impetigo in children and adolescents
(Dermatology, 2020)Background: Ozenoxacin is a topical antibiotic approved in Europe to treat non-bullous impetigo in adults and children aged ≥6 months. This analysis evaluated the efficacy and safety of ozenoxacin in ... -
Perception of quality of care of patients with potentially severe diseases evaluated at a distinct quick diagnostic delivery model: a cross-sectional study
(BMC Health Services Research, 2015-09-30)Background: Although hospital-based outpatient quick diagnosis units (QDU) are an increasingly recognized cost-effective alternative to hospitalization for the diagnosis of potentially serious diseases, ... -
The persistent breach between evidence and practice in the prevention of surgical site infection. Qualitative study
(International Journal of Surgery, 2020)Background: Despite the dissemination of guidelines for surgical site infection (SSI) prevention, a gap between the theoretical measures and their compliance persists. Accurate estimates of the ... -
Phakomatosis pigmentovascularis cesioflammea
(Journal of Respiratory Research, 2019)nCPAP-induced nose skin injury is a common issue in NICUs all over the world. Damage may vary from simple hyperemia in the region of application of nasal cannulae up to complete destruction of the ... -
Pharmacological interventions for preventing complications in patients with idiopathic hypercalciuria: a systematic review
(Nefrología, 2022)Objective: To assess the effects of pharmacological interventions in patients with idiopathic hypercalciuria. Methods: We performed a search of multiple databases, trial registries, grey literature and ... -
Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex
(2019)CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that forms an active complex with cyclin Y (CCNY). Although both proteins have been recently ... -
Physical and mental health impact of the COVID-19 pandemic at first year in a Spanish adult cohort
(Scientific Reports, 2023)The COVID-19 pandemic and the political and health measures have profoundly affected the health of our populations. However, very few studies have been published assessing its impact using a prospective ...