Browsing Ciències de la Salut by Title

Now showing items 312-331 of 734

    • Genetic and clinical heterogeneity in thirteen new cases with aceruloplasminemia. Atypical anemia as a clue for an early diagnosis 

      Vila Cuenca, Marc; Marchi, Giacomo; Barqué, Anna; Esteban-Jurado, Clara; Marchetto, Alessandro; Giorgetti, Alejandro; Chelban, Viorica; Houlden, Henry; Wood, Nicholas W.; Piubelli, Chiara; Dorigatti Borges, Marina; Martins de Albuquerque, Dulcinéia; Yotsumoto Fertrin, Kleber; Jové-Buxeda, Ester; Sanchez-Delgado, Jordi; Baena-Díez, Neus; Burnyte, Birute; Utkus, Algirdas; Busti, Fabiana; Kaubrys, Gintaras; Suku, Eda; Kowalczyk, Kamil; Karaszewski, Bartosz; Porter, John B.; Pollard, Sally; Eleftheriou, Perla; Bignell, Patricia; Girelli, Domenico; Sanchez, Mayka (International Journal of Molecular Sciences, 2020)
      Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation ...

    • Genetic screening for TLR7 variants in young and previously healthy men with severe COVID-19 

      Solanich, Xavier; Vargas-Parra, Gardenia; Van der Made, Caspar I.; Simons, Annet; Schuurs-Hoeijmakers, Janneke; Antolí, Arnau; Del Valle, Jesús; Rocamora-Blanch, Gemma; Setién, Fernando; Esteller, Manel; Van Reijmersdal, Simon V.; Riera-Mestre, Antoni; Sabater-Riera, Joan; Capellà, Gabriel; Van de Veerdonk, Frank L.; Van der Hoven, Ben; Corbella Virós, Xavier; Hoischen, Alexander; Lázaro, Conxi (Frontiers in Immunology, 2021)
      Introduction: Loss-of-function TLR7 variants have been recently reported in a small number of males to underlie strong predisposition to severe COVID-19. We aimed to determine the presence of these rare ...

    • Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis 

      Leon, Kristoffer E.; Schubert, Ryan D.; Casas-Alba, Didac; Hawes, Isobel A.; Ramachandran, Prashanth S.; Ramesh, Akshaya; Pak, John E.; Wu, Wesley; Cheung, Carly K.; Crawford, Emily D.; Khan, Lillian M.; Launes, Cristian; Sample, Hannah A.; Zorn, Kelsey C.; Cabrerizo, María; Valero-Rello, Ana; Langelier, Charles; Muñoz-Almagro, Carmen; DeRisi, Joseph L.; Wilson, Michael R. (Neurology: Neuroimmunology & Neuroinflammation, 2020)
      Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ...

    • Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex 

      Mir, Joan Francesc; Zagmutt, Sebastián; Lichtenstein, Mathieu P.; García-Villoria, Judit; Weber, Minéia; Gracia, Ana; Fabriàs, Gemma; Casas, Josefina; López, Miguel; Casals i Farré, Núria; Ribes, Antònia; Suñol, Cristina; Herrero Rodríguez, Laura; Serra, Dolors (Springer Nature, 2018)
      Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...

    • Growth rate as a direct regulator of the start network to set cell size 

      Aldea Malo, Martí; Jenkins, Kirsten; Csikász-Nagy, Attila (Frontiers in Cell and Developmental Biology, 2017-05-26)
      Cells are able to adjust their growth and size to external inputs to comply with specific fates and developmental programs. Molecular pathways controlling growth also have an enormous impact in cell ...

    • Gut microbial dysbiosis in patients with Cushing’s disease in long-term remission. Relationship with cardiometabolic risk 

      Valassi, Elena; Chaysavanh, Manichanh; Amodru, Vincent; González Fernández, Pedro; Gaztambide, Sonia; Yañez, Francisca; Martel Duguech, Luciana; Puig Domingo, Manuel; Webb, Susan (Frontiers in Endocrinology, 2023)
      Background: Patients with Cushing’s disease (CD) in remission maintain an increased cardiovascular risk. Impaired characteristics of gut microbiome (dysbiosis) have been associated with several ...

    • Haemochromatosis patients' research priorities: Towards an improved quality of life 

      Romero-Cortadellas, Lídia; Venturi, Veronica; Martín-Sánchez, Juan Carlos; Toska, Ketil; Prince, Dianne; Butzeck, Barbara; Porto, Graça; Thorm Milman, Nils; HI/EFAPH Survey Committee; Sánchez, Mayka (Health Expectations, 2023)
      Background: Chronic diseases are associated with a range of functional and psychosocial consequences that can adversely affect patients' quality of life (QoL). Haemochromatosis (HC) is a genetically ...

    • Healthy aging and late-life depression in Europe: Does migration matter? 

      Bayés Marín, Ivet; Fernández, Daniel; Ayuso-Mateos, Jose Luis; Leonardi, Matilde; Tobiasz-Adamczyk, Beata; Seppo, Koskinen; Sanchez-Niubo, Albert; Cristóbal-Narváez, Paula (2022)
      There is limited research examining the impact of risk and protective factors on late-life depression using large population-based datasets, particularly those examining differences among older migrants ...

    • Heart rate variability, exercise capacity and levels of dailyphysical activity in children and adolescents withmild-to-moderate cystic ̄brosis 

      De Freitas Coelho, Pitiguara; Ribeiro Batista Barbosa, Roberta; Dos Santos Lugao, Rodrigo; Mayrink Gonçalves Liberato, Fernanda; Reis Vidal, Pâmela; de Cássia Nunes Cruz Melotti, Roberta; Fagundes Donadio, Márcio Vinícius (Hong Kong Physiotherapy Journal, 2022)
      Background: Autonomic nervous system balance is altered in cystic fibrosis (CF), although its influence on physical fitness has been poorly explored. Objective: This study aimed to evaluate the association ...

    • Heterotopía, multiversos y viajes en el tiempo: la representación de la ciencia en Futurama y en Rick & Morty 

      Vidal-Mestre, Montserrat; Freire-Sánchez, Alfonso (Fotocinema. Revista científica de cine y fotografía, 2023)
      Esta investigación pretende detectar, codificar y cuantificar los principales temas y problemas científicos presentados en las series animadas de humor adulto Futurama y Rick and Morty con el objetivo ...

    • Hidden costs in breast cancer-related lymphedema 

      Martínez-Jaimez, Patricia; Masia, Jaume; Carlos, G. Forero; Fuster, Pilar; Monforte-Royo, Cristina (Elsevier, 2021)
      Breast cancer is the most common neoplastic process in women, with an incidence of 2,088,849 cases in 2018, and an overall 5-year survival of 90% and a 10-year survival of 83%.1 Lymphedema secondary to ...

    • High effectiveness of a 14-day concomitant therapy for helicobacter pylori treatment in primary care. An observational multicenter study 

      Olmedo, Llum; Azagra, Rafael; Aguyé, Amada; Pascual, Marta; Calvet, Xavier; Gené Tous, Emilio Miguel (Journal of Clinical Medicine, 2020)
      Background: The current cure rates with triple therapy combining a proton-pump inhibitor, amoxicillin and clarithromycin are unacceptably low. Aims: To evaluate the efficacy of a 14-day concomitant ...

    • High effectiveness of a 14-day concomitant therapy for Helicobacter pylori treatment in primary care. An observational multicenter study 

      Olmedo, Llum; Azagra, Rafael; Aguyé, Amada; Pascual, Marta; Calvet, Xavier; Gené, Emili (Journal of Clinical Medicine, 2020)
      Background: The current cure rates with triple therapy combining a proton-pump inhibitor, amoxicillin and clarithromycin are unacceptably low. Aims: To evaluate the efficacy of a 14-day concomitant ...

    • High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study 

      Hernandez, Gonzalo; Vaquero Collado, Concepción; García Plaza, Susana; Villasclaras Pacheco, Ana; Pardo Rey, Candido; De la Fuente O'Connor, Eugenia; Cuena, Rafael; González Arenas, Paloma; Fernández Fernández, Rafael (International Journal of Critical Care and Emergency Medicine, 2015-12-31)
      Objective: To determine the impact of delivering high flow conditioned oxygen therapy (HFO) through nasal cannula on prevention of reintubation in mechanically ventilated (MV) critically ill patients. ...

    • High red blood cell distribution width as a marker of hospital mortality after ICU discharge: a cohort study 

      Fernandez, Rafael; Cano Hernandez, Silvia; Catalan, Ignacio; Rubio Sanchiz, Olga; Subirà Cuyàs, Carles; Masclans, Jaume; Rognoni, Gina; Ventura, Lara; Macharete, Caroline; Winfield, Len; Alcoverro, Josep Mª. (Journal of Intensive Care, 2018-11-16)
      Background: High red blood cell distribution width (RDW) is associated with worse outcome in diverse scenarios, including in critical illness. The Sabadell score (SS) predicts in-hospital survival after ...

    • High-dose methylprednisolone pulses for 3 days vs. low-dose dexamethasone for 10 days in severe, non-critical COVID-19: a retrospective propensity score matched analysis 

      Mora-Luján, José María; Tuells, Manel; Montero, Abelardo; Formiga, Francesc; Homs, Narcís A.; Albà-Albalate, Joan; Corbella Virós, Xavier; Rubio-Rivas, Manuel (Journal of Clinical Medicine, 2021)
      Corticosteroids are largely recommended in patients with severe COVID-19. However, evidence to support high-dose methylprednisolone (MP) pulses is not as robust as that demonstrated for low-dose ...

    • High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial 

      Fernandez, Rafael; Subirà Cuyàs, Carles; Frutos‑Vivar, Fernando; Rialp, Gemma; Laborda, Cesar; Masclans, Joan Ramon; Lesmes, Amanda; Panadero, Luna; Hernandez, Gonzalo (Annals of Intensive Care, 2017-05-02)
      Background: Extubation failure is associated with increased morbidity and mortality, but cannot be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation respiratory failure ...

    • High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial 

      Marco, Ester; Ramírez-Sarmiento, Alba L; Coloma, Ana; Sartor, Monique; Comin-Colet, Josep; Vila, Joan; Enjuanes, Cristina; Bruguera, Jordi; Escalada, Ferran; Gea, Joaquim; Orozco-Levi, Mauricio (European Journal of Heart Failure, 2014)
      Aims: The purpose of this study was to evaluate the effectiveness, feasibility, and safety of a 4-week high-intensity inspiratory muscle training (hi-IMT) in patients with chronic heart failure (CHF). ...

    • Hip range of motion and strength in male athletes with stage 1 osteitis pubis: a cross-sectional and correlational study 

      Ceballos-Laita, Luis; Hernando-Garijo, Ignacio; Medrano-de-la-Fuente, Ricardo; Mingo-Gómez, Maria Teresa; Carrasco-Uribarren, Andoni; Jiménez, Sandra (International Journal of Environmental Reseacrh and Public Health, 2022)
      Background: The objectives of this study were: (1) to determine whether athletes with stage 1 osteitis pubis (OP) present differences in hip range of motion (ROM) and muscle strength, between both sides ...

    • Histological comparison of in vitro and in vivo development of peripheral posterior capsule opacification in human donor tissue 

      Ribeiro Koch, Camila; D'Antin, Justin Christopher; Tresserra, Francisco; Barraquer, Rafael Ignasi; Michael, Ralph (Experimental Eye Research, 2019)
      In order to study the mechanisms involved in the development of posterior capsule opacification (PCO) we compared in vivo developed PCO with PCO formed in tissue culture with focus on the periphery of ...