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Functional Brain Connectivity Prior to the COVID-19 Outbreak Moderates the Effects of Coping and Perceived Stress on Mental Health Changes: A First Year of COVID-19 Pandemic Follow-up Study
(2023)The COVID-19 pandemic provides a unique opportunity to investigate the psychological impact of a global major adverse situation. Our aim was to examine, in a longitudinal prospective study, the demographic, ... -
Functional consequences of transferrin receptor-2 mutations causing hereditary hemochromatosis type 3
(Molecular Genetics & Genomic Medicine, 2015)Hereditary hemochromatosis (HH) type 3 is an autosomal recessive disorder of iron metabolism characterized by excessive iron deposition in the liver and caused by mutations in the transferrin receptor ... -
Functional genomics approaches to elucidate vulnerabilities of intrinsic and acquired chemotherapy resistance
(Cells, 2021)Drug resistance is a commonly unavoidable consequence of cancer treatment that results in therapy failure and disease relapse. Intrinsic (pre-existing) or acquired resistance mechanisms can be drug-specific ... -
Functional massage of the teres major muscle in patients with subacromial impingement syndrome: a randomized controlled case series study
(International Journal of Medical and Pharmaceutical Case Reports, 2016)Objective: the purpose of the present study was to analyze the concurrent validity and reliability of a force platform clinical COBS Feedback® for the estimation of the height of vertical jumps. Design: ... -
Functional performance in the modified shuttle test in children and adolescents with cystic fibrosis
(Revista Paulista de Pediatria, 2021)Objective: To evaluate factors associated with the performance of children and adolescents with cystic fibrosis (CF) in the Modified Shuttle Test (MST) and compare it with healthy children and adolescents. ... -
Gender commonalities and differences in risk and protective factors of suicidal thoughts and behaviors: a cross-sectional study of Spanish university students
(Depression and Anxiety, 2019-11)AIM: To assess gender differences in the association between risk/protective factors and suicidal thoughts and behaviors (STB); and whether there is any gender-interaction with those factors and STB; ... -
Gender differences in health-related quality of life in patients with systolic heart failure: results of the VIDA multicenter study
(Journal of Clinical Medicine, 2020-08-31)Previous studies have shown that heart failure is associated with worse health-related quality of life (HRQoL). The existence of differences according to gender remains controversial. We studied 1028 ... -
Gender differences in hereditary hemorrhagic telangiectasia severity
(Orphanet Journal of Rare Diseases, 2020)Background: Gender differences in organ involvement and clinical severity have been poorly described in hereditary hemorrhagic telangiectasia (HHT). The aim of this study was to describe differences in ... -
Gender differences in labour losses associated with smoking-related mortality
(International Journal of Environmental Research and Public Health, 2019-09-28)The aim of this paper was to estimate the number of premature deaths, years of potential productive life lost (YPPLL) and labour losses attributable to tobacco smoking due to premature death by gender ... -
Gender differences in suicidal behavior in adolescents and young adults: systematic review and meta-analysis of longitudinal studies
(International Journal of Public Health, 2019)Objectives: To assess the association between gender and suicide attempt/death and identify gender-specific risk/protective factors in adolescents/young adults. Methods: Systematic review (5 databases ... -
Genetic and clinical heterogeneity in thirteen new cases with aceruloplasminemia. Atypical anemia as a clue for an early diagnosis
(International Journal of Molecular Sciences, 2020)Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation ... -
Genetic screening for TLR7 variants in young and previously healthy men with severe COVID-19
(Frontiers in Immunology, 2021)Introduction: Loss-of-function TLR7 variants have been recently reported in a small number of males to underlie strong predisposition to severe COVID-19. We aimed to determine the presence of these rare ... -
Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis
(Neurology: Neuroimmunology & Neuroinflammation, 2020)Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ... -
Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
(Springer Nature, 2018)Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ... -
Growth rate as a direct regulator of the start network to set cell size
(Frontiers in Cell and Developmental Biology, 2017-05-26)Cells are able to adjust their growth and size to external inputs to comply with specific fates and developmental programs. Molecular pathways controlling growth also have an enormous impact in cell ... -
Gut microbial dysbiosis in patients with Cushing’s disease in long-term remission. Relationship with cardiometabolic risk
(Frontiers in Endocrinology, 2023)Background: Patients with Cushing’s disease (CD) in remission maintain an increased cardiovascular risk. Impaired characteristics of gut microbiome (dysbiosis) have been associated with several ... -
Haemochromatosis patients' research priorities: Towards an improved quality of life
(Health Expectations, 2023)Background: Chronic diseases are associated with a range of functional and psychosocial consequences that can adversely affect patients' quality of life (QoL). Haemochromatosis (HC) is a genetically ... -
Healthy aging and late-life depression in Europe: Does migration matter?
(2022)There is limited research examining the impact of risk and protective factors on late-life depression using large population-based datasets, particularly those examining differences among older migrants ... -
Heart rate variability, exercise capacity and levels of dailyphysical activity in children and adolescents withmild-to-moderate cystic ̄brosis
(Hong Kong Physiotherapy Journal, 2022)Background: Autonomic nervous system balance is altered in cystic fibrosis (CF), although its influence on physical fitness has been poorly explored. Objective: This study aimed to evaluate the association ... -
Heterotopía, multiversos y viajes en el tiempo: la representación de la ciencia en Futurama y en Rick & Morty
(Fotocinema. Revista científica de cine y fotografía, 2023)Esta investigación pretende detectar, codificar y cuantificar los principales temas y problemas científicos presentados en las series animadas de humor adulto Futurama y Rick and Morty con el objetivo ...