• SIRT1 regulates hepatic vldlr levels 

      Peyman, Mona; Babin-Ebell, Anna; Rodríguez Rodríguez, Rosalía; Rigon, Matilde; Aguilar-Recarte, David; Villarroya, Joan; Planavila, Anna; Villarroya, Francesc; Palomer, Xavier; Barroso, Emma; Vázquez-Carrera, Manuel (Cell Communication and Signaling, 2024)
      Background: Endoplasmic reticulum (ER) stress-mediated increases in the hepatic levels of the very low-density lipoprotein (VLDL) receptor (VLDLR) promote hepatic steatosis by increasing the delivery ...
    • SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2 

      Barroso, Emma; Rodríguez-Rodríguez, Rosalía; Zarei, Mohammad; Pizarro-Delgado, Javier; Planavila, Anna; Palomer, Xavier; Villarroya, Francesc; Vázquez-Carrera, Manuel (Cell Communication and Signaling18;147, 2020-09-10)
      Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...