Visualitzant Ciències de la Salut per autor/a "Herrero Rodríguez, Laura"

Ara mostrant els elements 1-5 de 5

    • CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity 

      Rodríguez-Rodríguez, Rosalía; Miralpeix Monclús, Cristina; Fosch, Anna; Pozo Ariza, Macarena; Calderón-Domínguez, María; Perpinyà, Xavier; Vellvehí, Miquel; López, Miguel; Herrero Rodríguez, Laura; Serra, Dolors; Casals i Farré, Núria (Molecular Metabolism, 2019-01)
      Objective: Carnitine palmitoyltransferase 1C (CPT1C) is implicated in central regulation of energy homeostasis. Our aim was to investigate whether CPT1C in the ventromedial nucleus of the hypothalamus ...

    • Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex 

      Mir, Joan Francesc; Zagmutt, Sebastián; Lichtenstein, Mathieu P.; García-Villoria, Judit; Weber, Minéia; Gracia, Ana; Fabriàs, Gemma; Casas, Josefina; López, Miguel; Casals i Farré, Núria; Ribes, Antònia; Suñol, Cristina; Herrero Rodríguez, Laura; Serra, Dolors (Springer Nature, 2018)
      Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...

    • Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice 

      Miralpeix Monclús, Cristina; Fosch, Anna; Casas, Josefina; Baena, Miguel; Herrero Rodríguez, Laura; Serra, Dolors; Rodríguez-Rodríguez, Rosalía; Casals i Farré, Núria (Journal of Lipid Research, 2019-07)
      The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain ...

    • Increased infammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice 

      Alcalá, Martín; Calderón-Domínguez, María; Bustos, Eduviges; Ramos, Pilar; Casals i Farré, Núria; Serra, Dolors; Viana, Marta; Herrero Rodríguez, Laura (Scientific Reports, 2017-11-22)
      Obesity is associated with severe metabolic diseases such as type 2 diabetes, insulin resistance, cardiovascular disease and some forms of cancer. The pathophysiology of obesity-induced metabolic diseases ...

    • Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD 

      Weber, Minéia; Mera, Paula; Casas, Josefina; Salvador, Javier; Rodríguez, Amaia; Alonso, Sergio; Sebastián, David; Soler-Vázquez, M. Carmen; Montironi, Carla; Recalde, Sandra; Fucho, Raquel; Calderón-Domínguez, María; Mir, Joan Francesc; Bartrons, Ramon; Escola-Gil, Joan Carles; Sánchez-Infantes, David; Zorzano, Antonio; Llorente-Cortes, Vicenta; Casals i Farré, Núria; Valentí, Víctor; Frühbeck, Gema; Herrero Rodríguez, Laura; Serra, Dolors (Federation of American Societies for Experimental Biology, 2020)
      The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high‐fat ...