Browsing Ciències de la Salut by Author "Lázaro, Blanca"

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    • Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response 

      Samper Martín, Bàrbara; Sarrias, Ana; Lázaro, Blanca; Pérez-Montero, Marta; Rodríguez-Rodríguez, Rosalía; P.C. Ribeiro, Mariana; Bañón, Aitor; Wolfgeher, Donald; Jessen, Henning J.; Alsina, Berta; Clotet Erra, Josep; Kron, Stephen J.; Saiardi, Adolfo; Jiménez, Javier; Bru Rullo, Samuel (Cell Reports, 2021)
      Polyphosphate (polyP) is a polymer of hundreds of phosphate residues present in all organisms. In mammals, polyP is involved in crucial physiological processes, including coagulation, inflammation, and ...

    • Protocol to quantify polyphosphate in human cell lines using a tagged PPBD peptide 

      Jiménez, Javier; Lázaro, Blanca; Sarrias, Ana; Tadeo, Francisco J.; Pérez-Montero, Marta; Clotet, Josep; Bru, Samuel (STAR Protocols, 2022)
      Polyphosphate (polyP) is an evolutionarily conserved polymer of phosphates that is difficult to study in human cells because of its low concentration and high lability. First, we described how to express ...