Listando Ciències de la Salut por autor/a "Villanueva-Cañas, José Luis"
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Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
Pickup, Katherine E.; Pardow, Felicitas; Carbonell-Caballero, José; Lioutas, Antonios; Villanueva-Cañas, José Luis; Wright, Roni H.G.; Beato, Miguel (Cancers, 2019)The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have ... -
Hormone-control regions mediate steroid receptor–dependent genome organization
Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo P.; Carbonell-Caballero, José; Sharma, Priyanka; Villanueva-Cañas, José Luis; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni H.G.; Beato, Miguel (Genome Research, 2019)In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...