Polymeric additives to enhance the functional properties of calcium phosphate cements
Author
Pérez Antoñanzas, Roman
Hae-Won, Kim
Ginebra Molins, Maria Pau
Publication date
2012-03-20ISSN
2041-7314
Abstract
The vast majority of materials used in bone tissue engineering and regenerative medicine are based on calcium phosphates due to their similarity with the mineral phase of natural bone. Among them, calcium phosphate cements, which are composed of a powder and a liquid that are mixed to obtain a moldable paste, are widely used. These calcium phosphate cement pastes can be injected using minimally invasive surgery and adapt to the shape of the defect, resulting in an entangled network of calcium phosphate crystals. Adding an organic phase to the calcium phosphate cement formulation is a very powerful strategy to enhance some of the properties of these materials. Adding some water-soluble biocompatible polymers in the calcium phosphate cement liquid or powder phase improves physicochemical and mechanical properties, such as injectability, cohesion, and toughness. Moreover, adding specific polymers can enhance the biological response and the resorption rate of the material. The goal of this study is to overview the most relevant advances in this field, focusing on the different types of polymers that have been used to enhance specific calcium phosphate cement properties.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
611 - Anatomy. Human and comparative anatomy
Keywords
Calcium phosphate cement
Ciment de fosfat de calci
Hidroxiapatito
Hydroxyapatite
Hidroxiapatita
Polymers
Polímers
Polímeros
Pages
20
Publisher
Journal of Tissue Enineering
Citation
Perez, R. A., Kim, H. W., & Ginebra, M. P. (2012). «Polymeric additives to enhance the functional properties of calcium phosphate cements». Journal of tissue engineering, vol. 3, núm. 1, art. 2041731412439555. Disponible en: <https://journals.sagepub.com/doi/10.1177/2041731412439555>. Fecha de acceso: 21 oct. 2019. DOI: 10.1177/2041731412439555
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/