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Mostrando ítems 171-180 de 429
Methylprednisolone pulses plus tacrolimus in addition to standard of care vs. standard of care alone in patients with severe COVID-19. A randomized controlled trial
(Frontiers Media, 2021)
Introduction: Severe lung injury is triggered by both the SARS-CoV-2 infection and the subsequent host-immune response in some COVID-19 patients. Methods: We conducted a randomized, single-center, ...
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Rockefeller University Press, 2020-09)
Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
Self-learning methodology in simulated environments (MAES©) as a learning tool in perioperative nursing. An evidence-based practice model for acquiring clinical safety competencies
(MDPI, 2021)
Background: The self-learning Methodology in Simulated Environments (Spanish acronym: MAES©, (Murcia, Spain) is a type of self-directed and collaborative training in health sciences. The objective of ...
Predicting clinical outcome with phenotypic clusters in COVID-19 pneumonia: an analysis of 12,066 hospitalized patients from the spanish registry SEMI-COVID-19
(MDPI, 2020)
(1) Background: Different clinical presentations in COVID-19 are described to date, from mild to severe cases. This study aims to identify different clinical phenotypes in COVID-19 pneumonia using cluster ...
The wish to hasten death in patients with life-limiting conditions. A systematic overview
(Elsevier, 2024)
Context: A systematic review of the wish to hasten death among people with life-limiting conditions was published in 2011. Since then, other reviews and primary studies have been published that have ...
Development of a Guide to Multidimensional Needs Assessment in the Palliative Care Initial Encounter (MAP)
(Elsevier, 2023-10)
Context: Ensuring patient-centered palliative care requires a comprehensive assessment of needs beginning in the initial encounter. However, there is no generally accepted guide for carrying out this ...
New insights of SF1 neurons in hypothalamic regulation of obesity and diabetes
(MDPI, 2021)
Despite the substantial role played by the hypothalamus in the regulation of energy balance and glucose homeostasis, the exact mechanisms and neuronal circuits underlying this regulation remain poorly ...
Risk factors associated with inappropriate empirical antimicrobial treatment in bloodstream infections. A cohort study
(Frontiers Media, 2023)
Introduction: Bloodstream infections (BSI) are a major cause of mortality all over the world. Inappropriate empirical antimicrobial treatment (i-EAT) impact on mortality has been largely reported. ...
Correlation between neck muscle endurance tests, ultrasonography, and self-reported outcomes in women with low cervical disability and neck pain
(MDPI, 2023)
Background: Neck pain (NP) is a frequent condition in women, characterized by exhibiting distinct clinical manifestations such as the presence of deep neck (DN) muscle weakness. Endurance and ultrasonography ...