Visualitzant Articles per matèria "61"
Ara mostrant els elements 1-20 de 704
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A 3-dimensional histology computer model of malignant melanoma and its implications for digital pathology
(European Journal of Cancer, 2023)Background: Historically, cancer diagnoses have been made by pathologists using two-dimensional histological slides. However, with the advent of digital pathology and artificial intelligence, slides are ... -
90 years of progesterone: molecular mechanisms of progesterone receptor action on the breast cancer genome
(Journal of Molecular Endocrinology, 2020)Gene regulation by steroid hormones has been at the forefront in elucidating the intricacies of transcriptional regulation in eukaryotes ever since the discovery by Karlson and Clever that the insect ... -
A barbed suture repair for flexor tendons: a novel technique with no exposed barbs
(Plastic and Reconstructive Surgery Global Open, 2014-10-23)Background: Barbed suture technology has shown promise in flexor tendon repairs, as there is an even distribution of load and the need for a knot is eliminated. We propose that a quick and simple, ... -
A linear lesion in a child with atopic dermatitis: not a coincidence
(Clinical Case Reports, 2019-07-25)A blaschkolinear lesion in a patient with atopic dermatitis can be a superimposed segmental manifestation of this polygenic disorder. Knowledge of this phenomenon, presence of less severe, disseminated, ... -
A mutation in the iron-responsive element of ALAS2 is a modifier of disease severity in a patient suffering from CLPX associated erythropoietic protoporphyria
(Haematologica, 2021)Porphyrias are a group of eight genetically distinct disorders, each resulting from a partial deficiency or gain-offunction of a specific enzyme in the heme biosynthetic pathway.1 Porphyrias are inherited ... -
A nucleotide-based drug protects against glutamate- and MPP+ -induced neurotoxicity
(Neuroscience & Medicine, 2011)Nucleo CMP Forte® is a nucleotide-based drug consisting of cytidinemonophosphate, uridinemonophosphate, uridin-ediphosphate and uridinetriphosphate. It has been prescribed for peripheral nervous system ... -
A path analysis model of self- vs. educational-context- regulation as combined predictors of well-being in spanish college students
(International Journal of Environmental Reseacrh and Public Health, 2022)Previous literature has established the importance of personal and contextual factors in college students’ trajectories. Following the Self- vs. External-Regulation Behavior Theory (2021) and the 3P ... -
A perspective on the role of physiological stresses in cancer, diabetes and cognitive disease as environmental diseases
(Frontiers in Molecular Biosciences, 2023)With rapid industrialization, urbanization, and climate change, the impact of environmental factors on human health is becoming increasingly evident and understanding the complex mechanisms involved is ... -
A quick diagnosis unit as an alternative to conventional hospitalization in a tertiary public hospital: a descriptive study
(Polish Archives of Internal Medicine, 2013-09-24)Introduction: Reports indicate that a significant number of patients admitted to internal medicine units could be studied on an outpatient basis. Objectives: This article assesses a quick diagnosis unit ... -
A radiographic and clinical comparison of immediate vs. early loading (4 weeks) of implants with a new thermo-chemically treated surface: a randomized clinical trial
(International Journal of Environmental Research and Public Health, 2021)Background: Implant dentistry has evolved over time, resulting in better treatment outcomes for both patients and clinicians. The aim of this trial was to test whether the immediate loading of implants ... -
A self-calibrating and multiplexed electrochemical lab-on-a-chip for cell culture analysis and high-resolution imaging
(Lab on a Chip, 2020)In vitro analysis requires cell proliferation in conditions close to physiological ones. Lab-on-a-chip (LoC) devices simplify, miniaturize and automate traditional protocols, with the advantages of being ... -
A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Cell Reports, 2012-10-25)Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ... -
Aberrantly spliced mRNAs of the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene with a donor splice-site point mutation produce hereditary HL deficiency
(Journal of Lipid Research, 1996-11)A novel point mutation in the 3-hydroxy-3methyl-glutaryl coenzyme A lyase gene was found in a Turkish patient with homozygous 3-hydroxy-3-methylglutaric acidemia. Amplification by RT-PCR of the mRNA ... -
Accuracy and safety of dry needling placement in the popliteus muscle: a cadaveric study
(International Journal of Clinical Practice, 2021)Background: The popliteus muscle attaches posteriorly to the joint capsule of the knee. Although it is an important rotational stabiliser and has been implicated in various knee pathologies, research ... -
Accuracy of online survey assessment of mental disorders and suicidal thoughts and behaviors in spanish university students. Results of the WHO world mental health international college student initiative
(PLoS One, 2019)Objective: To assess the accuracy of WMH-ICS online screening scales for evaluating four common mental disorders (Major Depressive Episode[MDE], Mania/Hypomania[M/H], Panic Disorder[PD], Generalized ... -
Aceptación y preferencia de los métodos de distracción audiovisual utilizados en odontopediatría por parte del paciente pediátrico y padres
(Odontología Pediátrica, 2020)Objetivo: determinar la preferencia de los niños y de los padres por los diferentes métodos de distracción audiovisual utilizados en odontopediatría. Material y métodos: estudio descriptivo transversal ... -
Active school-based interventions to interrupt prolonged sitting improve daily physical activity: a systematic review and meta-analysis
(International Journal of Environmental Research and Public Health, 2022)Background: Sedentary behavior (SB) is a negative routine for health, especially during advancing age. Promoting an active lifestyle and reducing SB is a global endeavor. The aim of this study was to ... -
Acute and chronic effects of competition on ankle dorsiflexion ROM in professional football players
(European Journal of Sport Science, 2020)The aim of this study was to investigate the acute (a football match) and chronic (a whole season) effects of competition on ankle dorsiflexion ROM in professional football players. Forty football players ... -
Adams-Oliver syndrome
(Journal of Respiratory Research, 2019)A term infant born in a resource-poor setting (Mozambique) presented with extensive disepithelization of the cranial vertex with absent underlying bony plate, disepithelization of the posterior median ... -
Adaptación y estudio de propiedades métricas de un cuestionario de valoración del sueño para lactantes y preescolares
(Anales de Pediatría, 2018-10)Introducción: Aunque las alteraciones del sueño en lactantes y preescolares son comunes, no se dispone de un instrumento en español adecuadamente validado para su estudio. El Brief Infant Sleep Questionnaire ...