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Junctional epithelium and hemidesmosomes: tape and rivets for solving the “percutaneous device dilemma” in dental and other permanent implants
(Elsevier, 2022-12)
The percutaneous device dilemma describes etiological factors, centered around the disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant percutaneous device infection. ...
Functional signatures of ex-vivo dental caries onset
(Taylor & Francis Group, 2022)
Background: The etiology of dental caries remains poorly understood. With the advent of next-generation sequencing, a number of studies have focused on the microbial ecology of the disease. However, ...
Relevant aspects of piranha passivation in Ti6Al4V alloy dental meshes
(MDPI, 2022)
Passivation of titanium alloy dental meshes cleans their surface and forms a thin layer of protective oxide (TiO2) on the surface of the material to improve resistance to corrosion and prevent release ...
Development of standard protocols for biofilm-biomaterial interface testing
(Elsevier, 2022)
The oral biofilm is associated with the most common oral diseases such as caries, periodontitis, and peri-implantitis. It is also linked to failures of dental treatment approaches (eg, direct or indirect ...
Implant surface physicochemistry affects keratinocyte hemidesmosome formation
(John Wiley & Sons, 2023)
Previous studies have shown hydrophilic/hydrophobic implant surfaces stimulate/hinder osseointegration. An analogous concept was applied here using common biological functional groups on a model surface ...
Guiding bone formation using semi-onlay calcium phosphate implants in an ovine calvarial model
(John Wiley & Sons, 2022)
The restoration of cranio-maxillofacial deformities often requires complex reconstructive surgery in a challenging anatomical region, with abnormal soft tissue structures and bony deficits. In this ...
Surface immobilization chemistry of a laminin-derived peptide affects keratinocyte activity
(MDPI, 2020)
Many chemical routes have been proposed to immobilize peptides on biomedical device surfaces, and in particular, on dental implants to prevent peri-implantitis. While a number of factors affect peptide ...
Targeting the oral plaque microbiome with immobilized anti-biofilm peptides at tooth-restoration interfaces
(Public Library of Science, 2020)
Recurrent caries, the development of carious lesions at the interface between the restorative material and the tooth structure, is highly prevalent and represents the primary cause for failure of dental ...
Biomimetic mineralized hybrid scaffolds with antimicrobial peptides
(Elsevier, 2021-08)
Infection in hard tissue regeneration is a clinically-relevant challenge. Development of scaffolds with dual function for promoting bone/dental tissue growth and preventing bacterial infections is a ...
Culture and characterization of various porcine integumentary-connective tissue-derived mesenchymal stromal cells to facilitate tissue adhesion to percutaneous metal implants
(Springer Nature, 2021)
Background: Transdermal osseointegrated prosthesis have relatively high infection rates leading to implant revision or failure. A principle cause for this complication is the absence of a durable ...