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Listando por materia "Tissue engineering"

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    • A bioengineering approach for corneal endothelial regeneration. 

      Bosch Canals, Begoña María (Fecha de defensa: 2019-07-31)
      Nowadays, there are approximately 10 million people worldwide with visual impairment due to corneal diseases. Currently, the main therapeutic solution is the transplant of a donor's cornea. The great ...
    • Biofabrication of tissue engineering vascular systems 

      Zhang, Qiao; Bosch-Rué, Elia; Pérez Antoñanzas, Roman; Truskey, George A. (APL Bioengineering, 2021-05)
      Cardiovascular disease (CVD) is the leading cause of death among persons aged 65 and older in the United States and many other developed countries. Tissue engineered vascular systems (TEVS) can serve ...
    • Biological roles and delivery strategies for ions to promote osteogenic induction 

      Bosch-Rué, Elia; Diez-Tercero, Leire; Giordano-Kelhoffer, Barbara; Delgado, Luis M.; Bosch Canals, Begoña María; Hoyos Nogués, Mireia; Mateos-Timoneda, Miguel Angel; Tran, Phong A.; Gil Mur, Francisco Javier; Pérez Antoñanzas, Roman (Frontiers in Cell and Developmental Biology, 2021-01-14)
      Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ...
    • Characterization of a three-dimensional mucosal equivalent: similarities and differences with native oral mucosa 

      Tra, Wendy M. W.; W. van Neck, Johan; E. R. Hovius, Steven; J. V. M. van Osch, Gerjo; Perez Amodio, Soledad (Cells Tissues Organs, 2012)
      The aim of this study was to create and characterize a tissue-engineered mucosal equivalent (TEM) that closely resembles native mucosa. TEM consists of human primary keratinocytes and fibroblasts isolated ...
    • Computational modeling as a tool to investigate PPI: from drug design to tissue engineering 

      Perez, Juan J.; Pérez Antoñanzas, Roman; Perez, Alberto (Frontiers in Molecular Biosciences, 2021)
      Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the ...
    • Development of small tissue engineered blood vessels and their clinical and research applications 

      Bosch Rué, Elia; Zhang, Qiao; Truskey, George; Olmos Buitrago, Jennifer; Bosch Canals, Begoña Maria; Perez, Roman (Biofabrication, 2025-05-27)
      Since the first tissue engineered blood vessel (TEBV) was developed, different approaches, biomaterial scaffolds and cell sources have been used to obtain an engineered vessel as much similar as native ...
    • Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering 

      Rodríguez González, Raquel (Fecha de defensa: 2023-05-31)
      The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body ...
    • Evaluation of the immunomodulatory effects of cobalt, copper and magnesium ions in a pro inflammatory environment 

      Díez-Tercero, Leire; Delgado, Luis M.; Bosch-Rué, Elia; Pérez Antoñanzas, Roman (Scientific Reports, 2021)
      Biomaterials and scaffolds for Tissue Engineering are widely used for an effective healing and regeneration. However, the implantation of these scaffolds causes an innate immune response in which the ...
    • Nanotechnology in dentistry: prevention, diagnosis, and therapy 

      Abou Neel, Ensanya Ali; Bozec, Laurent; Pérez Antoñanzas, Roman; Kim, Hae-Won; Knowles, Jonathan C. (International Journal of Nanomedicine, 2015-10-08)
      Nanotechnology has rapidly expanded into all areas of science; it offers significant alternative ways to solve scientific and medical questions and problems. In dentistry, nanotechnology has been exploited ...
    • Oozing: an accessible technique to create 3D-printed scaffolds suitable for tissue engineering 

      Crespo Santiago, Juan; Delgado, Luis M.; Madariaga, Rafa; Millan , Laia; Chico, Oriol; Oliver, Pau; Pérez Antoñanzas, Román; Otero-Viñas, Marta (International Journal of Bioprinting, 2024)
      Tissue-engineered constructs require mimicking the extracellular matrix microenvironment of native tissue for better promoting cell growth. Commercial three-dimensional (3D) printers provide a versatile ...
    • Three dimensional porous scaffolds derived from collagen, elastin and fibrin proteins orchestrate adipose tissue regeneration 

      Sawadkar, Prasad; Mandakhbayar, Nandin; Patel, Kapil D.; Olmas Buitrago, Jennifer; Hyun Kim, Tae; Rajasekar, Poojitha; Lali, Ferdinand; Kyriakidis, Christos; Rahmani, Benyamin; Mohanakrishnan, Jeviya; Dua, Rishbha; Greco, Karin; Lee, Jung-Hwan; Kim, Hae-Won; Knowles, Jonathan C.; García-Gareta, Elena (Journal of Tissue Engineering, 2021)
      Current gold standard to treat soft tissue injuries caused by trauma and pathological condition are autografts and off the shelf fillers, but they have inherent weaknesses like donor site morbidity, ...
    • Tissue-engineered mucosa is a suitable model to quantify the acute biological effects of ionizing radiation 

      Tra, W. M. W.; Tuk, B.; Van Neck, J. W.; Hovius, S. E. R.; Perez Amodio, Soledad (International Journal of Oral and Maxillofacial Surgery, 2025)
      The aim of this study was to evaluate the suitability of tissue-engineered mucosa (TEM) as a model for studying the acute effects of ionizing radiation (IR) on the oral mucosa. TEM and native non-keratinizing ...
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