Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
Autor/a
Rocas, Pau
Hoyos Nogués, Mireia
Rocas, Josep
Manero Planella, José María
Gil Mur, Francisco Javier
Albericio Palomera, Fernando
Mas Moruno, Carlos
Fecha de publicación
2015ISSN
2192-2640
Resumen
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa NPs results in an outstanding improvement of osteoblast adhesion and strong suppression of bacterial attachment. This strategy represents a powerful approach to enhance the osseointegration of implant materials.
Tipo de documento
Artículo
Versión del documento
Versión aceptada
Lengua
Inglés
Materias (CDU)
61 - Medicina
Palabras clave
Titani
Materials biomèdics
Implants
Materials nanoestructurats
Pèptids
Titanio
Materiales biomédicos
Implantes
Materiales nanoestructurados
Péptidos
Titanium
Biomedical materials
Implants
Nanostructured materials
Peptides
Páginas
5
Publicado por
Wiley
Colección
4;13
Publicado en
Advanced Healthcare Materials
Citación
Rocas, Pau; Hoyos Nogués, Mireia; Rocas, Josep [et al.]. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. Advanced Healthcare Materials, 2015, 4(13), p. 1-5. Disponible en: <https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201500245>. Fecha de acceso: 17 jun. 2020. DOI: 10.1002/adhm.201500245
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Derechos
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifi cations or adaptations are made.
Excepto si se señala otra cosa, la licencia del ítem se describe como https://creativecommons.org/licenses/by-nc-nd/4.0/
