Arxiu Digital UIC: Recent submissions
Now showing items 2381-2400 of 4309
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Recomanacions literàries (gener 2022)
(Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2022-01-19)T’agraden les novel•les distòpiques? Doncs avui et portem un dels millors clàssics d’aquest gènere, 1983 de George Orwell. Escrita l’any 1949, la història succeeix en un futur on existeix una dictadura ... -
Implementing technology in healthcare: insights from physicians
(BMC Medical Informatics and Decision Making, 2017)Background: Technology has significantly changed the way health organizations operate. However, the role it plays in healthcare systems remains unclear. This aim of this study was to evaluate the opinion ... -
Novel mutations in the ferritin-L iron-responsive element that only mildly impair IRP binding cause hereditary hyperferritinaemia cataract syndrome
(Orphanet Journal of Rare Diseases, 2013)Background: Hereditary Hyperferritinaemia Cataract Syndrome (HHCS) is a rare autosomal dominant disease characterized by increased serum ferritin levels and early onset of bilateral cataract. The disease ... -
SIREs: searching for iron-responsive elements
(Nucleic Acids Research, 2010-07)The iron regulatory protein/iron-responsive element regulatory system plays a crucial role in the post-transcriptional regulation of gene expression and its disruption results in human disease. IREs are ... -
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
(BMC Bioinformatics, 2010)Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations ... -
Dia Internacional de la Síndrome de l'Hemiplegia Alternant
(Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2022-01-18)La Síndrome de l'Hemiplegia Alternant és una malaltia neurològica crònica molt poc freqüent (1:1000000). S'inicia durant la infància, i es caracteritza pels atacs d'hemiparèsia (disminució de la força ... -
Genetic and clinical heterogeneity in thirteen new cases with aceruloplasminemia. Atypical anemia as a clue for an early diagnosis
(International Journal of Molecular Sciences, 2020)Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation ... -
Functional characterization of a novel non-coding mutation “Ghent +49A > G” in the iron-responsive element of L-ferritin causing hereditary hyperferritinaemia-cataract syndrome
(Scientific Reports, 2017)Hereditary hyperferritinaemia-cataract syndrome (HHCS) is a rare disorder usually caused by heterozygous mutations in the iron-responsive element (IRE) in the 5′ untranslated region (5′UTR) of the ... -
CoDysAn: a telemedicine tool to improve awareness and diagnosis for patients with congenital dyserythropoietic anemia
(Frontiers in Physiology, 2019)Congenital Dyserythropoietic Anemia (CDA) is a heterogeneous group of hematological disorders characterized by chronic hyporegenerative anemia and distinct morphological abnormalities of erythroid ... -
Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom
(PLoS One, 2014)Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The ... -
L-ferritin: one gene, five diseases; from hereditary hyperferritinemia to hypoferritinemia - report of new cases
(Pharmaceuticals, 2019)Ferritin is a multimeric protein composed of light (L-ferritin) and heavy (H-ferritin) subunits that binds and stores iron inside the cell. A variety of mutations have been reported in the L-ferritin ... -
Iron Regulation and the Cell Cycle: identification of an iron-responsive element in the 3′-untranslated region of human cell division cycle 14a mrna by a refined microarray-based screening strategy
(The Journal of Biological Chemistry, 2006)Iron regulatory proteins (IRPs) 1 and 2 post-transcriptionally control mammalian iron homeostasis by binding to iron-responsive elements (IREs), conserved RNA stem-loop structures located in the 5′- or ... -
Factors associated with depression and anxiety in adults ≥60 tears old during the COVID-19 pandemic: a systematic review
(International Journal of Environmental Research and Public Health, 2021)COVID-19 represents a threat to public health and the mental health of the aged population. Prevalence and risk factors of depression and anxiety have been reported in previous reviews in other populations; ... -
Covid-19, an opportunity to compare in-person and online teaching
(Revista Española de Educación Médica, 2021)For years it has been discussed the dichotomy between traditional in-person teaching versus online instruction. The lockdown, consequence of the Covid-19 pandemic, gave us an opportunity to gain evidence ... -
Immobilization of BMP-2 and VEGF within multilayered polydopamine-coated scaffolds and the resulting osteogenic and angiogenic synergy of co-cultured human mesenchymal stem cells and human endothelial progenitor cells
(International Journal of Molecular Sciences, 2020)We have previously reported the fabrication of a polycaprolactone and hydroxyapatite composite scaffold incorporating growth factors to be used for bone regeneration. Two growth factors were incorporated ... -
New mutations in HFE2 and TFR2 genes causing non HFE-related hereditary hemochromatosis
(Genes, 2021)Hereditary hemochromatosis (HH) is an iron metabolism disease clinically characterized by excessive iron deposition in parenchymal organs such as liver, heart, pancreas, and joints. It is caused by ... -
Sexennis d'Aneca
(Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2022-01-17)Avui s'obre el termini de presentació de sol·licituds de sexennis a través de la seu electrònica d'ANECA fins al pròxim 7 de febrer. Aquest dimecres 19 de gener ANECA oferirà una sèrie de videoconferències ... -
Multiple ion scaffold-based delivery platform for potential application in early stages of bone regeneration
(Materials, 2021)Bone has the intrinsic capacity to regenerate itself, as long as the damage is small, through the sequential stimulation of specific phases, such as angiogenesis followed by osteogenesis. However, when ... -
¿Qué hemos aprendido de las encuestas de la AEC, AECP y del Observatorio de Infección en Cirugía? Cumplimiento de las medidas de prevención de infección postoperatoria y comparación con las recomendaciones de la AEC
(Cirugía Española, 2021)Antes de planificar estrategias de mejora, es crucial conocer el grado de implementación de las medidas preventivas de infección postoperatoria. Se presentan los resultados agregados de 3 encuestas ... -
Surgeon-led 7-VINCut antibiotic stewardship intervention decreases duration of treatment and carbapenem use in a general surgery service
(Antibiotics, 2021)Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary ...