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Rol de CPT1C en la supervivencia de las células madre mesenquimales
(Universitat Internacional de Catalunya, 2016-09-06)
La carnitina palmitoiltransferasa 1C (CPT1C) pertenece a la familia de enzimas CPT1, las cuales controlan la entrada de ácidos grasos al lumen de la mitocondria para su posterior oxidación. Sin embargo, ...
CPT1C and endocannabinoids as hypothalamic players in early stages of obesity development
(Universitat Internacional de Catalunya, 2019-12-10)
Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, ...
CPT1C-dependent regulation of GluA1 trafficking under metabolic stress
(Universitat Internacional de Catalunya, 2019-12-10)
Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still ...
Papel de CPT1C en el desarrollo axonal y en el transporte de los endosomas tardíos
(Universitat Internacional de Catalunya, 2018-03-23)
La paraplejía espástica hereditaria agrupa un conjunto de desórdenes neurodegenerativos caracterizados por espasticidad y rigidez muscular. Todos ellos están relacionados clínica y patológicamente con ...
Role of CPT1C in breast cancer development and chemoresistance
(Universitat Internacional de Catalunya, 2021-07-14)
Carnitine palmitoyl transferase 1 (CPT1) are enzymes that catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, to transport long-chain fatty acids across intracellular membranes. CPT1C ...