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G1-Cdk modulation by time and stress
(Universitat Internacional de Catalunya, 2022-09-23)
The cell cycle is regulated at different layers of control in either homeostatic or non-homeostatic conditions. Hence, in
this work we analyse how time and stress modulate the cell cycle through the ...
Predicción mediante un enfoque bayesiano del consumo de tabaco y mortalidad por cáncer de pulmón en España.
(Universitat Internacional de Catalunya, 2016-11-24)
El consumo de tabaco es una de las mayores causas de morbimortalidad en el mundo. Además, el
cáncer de pulmón es una de las enfermedades más claramente vinculadas a este consumo.
La mortalidad por ...
Caracterización de complejos CDK-Ciclina atípicos humanos
(Universitat Internacional de Catalunya, 2018-03-15)
La desregulación en los mecanismos de control del ciclo celular es un evento indiscutiblemente asociado a la aparición de diversas patologías, entre las que destacan los procesos tumorales. Como principales ...
Hypothalamic Ceramide Levels regulated by CPT1C mediate the Orexigenic effect of Ghrelin
(Universitat Internacional de Catalunya, 2014-07-31)
Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of ...
CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation
(Universitat Internacional de Catalunya, 2022-09-23)
Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the
population with overweight has nearly tripled since 1975, and the tendency is still growing.
These data have an ...
Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: associated diseases and new target mRNAs (PPP1R1B)
(Universitat Internacional de Catalunya, 2022-09-23)
Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron
homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory ...
Increasing Forgiveness: design of two brief techniques based on the Social Learning Theory.
(Universitat Internacional de Catalunya, 2017-11-15)
Forgiveness is a human strength mainly helpful for the wellbeing of social relationships. Research has showed the potential benefits of forgiving for physical and mental health as well as for restoring ...
Control de la estabilidad de ciclinas de G1 por nutrientes
(Universitat Internacional de Catalunya, 2014-07-31)
El control del ciclo celular está altamente regulado mediante diferentes CDKs asociadas a ciclinas. En Saccharomyces cerevisiae, la CDK esencial Cdc28 es la que regula mayoritariamente este proceso. En ...
Strategies to induce vascularization: angiogenesis stimulation and tissue engineering blood vessels
(Universitat Internacional de Catalunya, 2021-01-25)
Angiogenesis, which results in a capillary network formation, is one of the crucial events that take place when there is tissue damage, being critical for successful tissue regeneration. It does not ...
Nudt3. La primera endopolifosfatasa humana
(Universitat Internacional de Catalunya, 2020-10-15)
El polifosfato inorgánico (polyP) es un polímero compuesto por cientos de residuos de fosfato (Pi) unidos por enlaces fosfoanhidro de alta energía. Esta molécula se encuentra en todos los organismos ...