Browsing Departament de Ciències Bàsiques (Biomedicina, Bioenginyeria, Psicologia) by Title
Now showing items 12-31 of 51
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CPT1C-dependent regulation of GluA1 trafficking under metabolic stress
(Date of defense: 2019-12-10)Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still ... -
Desarrollo de nuevos métodos para el análisis del polifosfato en células humanas
(Date of defense: 2023-11-20)Nombre / Nom / Name Ana Apellidos / Cognoms / Surname Sarrias Giménez Dirección de correo electrónico / Adreça de correu electrònic / email address (opcional / optional) anasargim@gmail.com Departamento ... -
Development of C75-CoA loaded polymeric micelles targeting brain CPT1A: A novel nanomedicine-based approach to fight obesity and cancer
(Date of defense: 2024-02-14)Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl ... -
Development of novel bioinks formulations based on supramolecular self-assembled hydrogels for tissue regeneration.
(Date of defense: 2023-05-16)The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also ... -
Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering
(Date of defense: 2023-05-31)The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body ... -
El polifosfat és un element clau durant la replicació del DNA.
(Date of defense: 2015-11-06)Throughout its lifespan, eukaryotic cells steadily consume free cytoplasmic orthophosphate to produce phospholipids and mRNA. However, during DNA synthesis, in a matter of minutes, cells require large ... -
Estudi de la ciclina atípica CCNI com a potencial activador de CDK6 en línies de càncer de mama
(Date of defense: 2022-02-09)Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament ... -
Evaluation of biomarkers for studying new challenges in tobacco control
(Date of defense: 2023-12-19)El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control ... -
Evaluation of the impact of Spanish smoking legislation on tobacco consumption and passive exposure
(Date of defense: 2018-03-14)In Spain, two smoke-free laws have been passed after the approval of the FCTC. In 2005, it came into effect a smoke-free legislation (Law 28/2005). This law was a great advance for public health in ... -
Expresión de factores de transcripción TCF7L2 durante la diferenciación in vitro de células de neuroblastoma inducida por el ácido retinoico.
(Date of defense: 2018-02-06)Las proteínas TCF7L2 (transcription factor 7-like 2) son un conjunto de factores de transcripción que participan en la vía Wnt y son responsables, entre otras funciones, del mantenimiento de las células ... -
Extracellular UTP signalling in Schwann cell migration: A novel role of the P2Y2 receptor
(Date of defense: 2013-09-24)Peripheral neuropaties are one of the major complications of the Peripheral Nervous System. Depsite the big importance of those pathologies, less drugs are effective for their treatment, and most of the ... -
Factores relacionados con el perdón: características de la ofensa, del ofensor y del ofendido.
(Date of defense: 2016-03-01)En el presente trabajo revisamos las diferentes variables que han sido asociadas al perdón. Son muchos los factores que influyen en que dicho proceso se lleve a cabo o no. Estudios previos han ... -
G1-Cdk modulation by time and stress
(Date of defense: 2022-09-23)The cell cycle is regulated at different layers of control in either homeostatic or non-homeostatic conditions. Hence, in this work we analyse how time and stress modulate the cell cycle through the ... -
Hypothalamic Ceramide Levels regulated by CPT1C mediate the Orexigenic effect of Ghrelin
(Date of defense: 2014-07-31)Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of ... -
Increasing Forgiveness: design of two brief techniques based on the Social Learning Theory.
(Date of defense: 2017-11-15)Forgiveness is a human strength mainly helpful for the wellbeing of social relationships. Research has showed the potential benefits of forgiving for physical and mental health as well as for restoring ... -
Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: associated diseases and new target mRNAs (PPP1R1B)
(Date of defense: 2022-09-23)Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory ... -
La ciclina CNTD2: un nuevo inductor del desarrollo tumoral
(Date of defense: 2018-07-26)El cáncer colorrectal (CRC) es uno de los cánceres más comunes en todo el mundo, con un 8-10% de estos tumores que presentan una mutación BRAF (V600E). Las ciclinas son oncogenes comúnmente desregulados ... -
La cronicidad en enfermedad mental: políticas y modelos de atención integrados y centrados en las personas y la comunidad
(Date of defense: 2023-12-14)La creciente prevalencia de enfermedades mentales y cronicidad orgánica genera una comorbilidad con impacto en la salud, calidad de vida y eficiencia de los modelos de atención. Se necesita un enfoque ... -
Localización del foramen mandibular: estudio anatómico mediante tomografía computarizada (TC)
(Date of defense: 2012-08-01)Para la mayoría de tratamientos dentales, es efectiva la utilización de técnicas anestésicas de tipo infiltrativo, consiguiendo el bloqueo efectivo del estímulo doloroso en todos los dientes de la arcada ... -
lux operon transformation of plastids in higher plants
(Date of defense: 2013-11-13)Este trabajo es parte de la investigación del Grupo de investigación de Arquitecturas Genéticas (2009 SGR 862). El objetivo global del grupo es investigar sobre las nuevas formas arquitectónicas y ...