dc.contributor.author | Muñoz, F. | |
dc.contributor.author | Haidar, Z. S. | |
dc.contributor.author | Puigdollers, Andreu | |
dc.contributor.author | Guerra, I. | |
dc.contributor.author | Padilla, M. Cristina | |
dc.contributor.author | Ortega, N. | |
dc.contributor.author | García, M. J. | |
dc.date.accessioned | 2024-05-24T08:14:17Z | |
dc.date.available | 2024-05-24T08:14:17Z | |
dc.date.issued | 2024 | |
dc.identifier.citation | Muñoz, F.; Haidar, Z. S.; Puigdollers, Andreu [et al.]. A novel Chilean salmon fish backbone-based nanoHydroxyApatite functional biomaterial for potential use in bone tissue engineering. Frontiers in Medicine, 2024, 11, 1330482. Disponible en: <https://www.frontiersin.org/articles/10.3389/fmed.2024.1330482/full>. Fecha de acceso: 24 may. 2024. DOI: 10.3389/fmed.2024.1330482 | ca |
dc.identifier.issn | 2296-858X | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/4250 | |
dc.description.abstract | Introduction: Given the ensuing increase in bone and periodontal diseases and defects, de novo bone repair and/or regeneration strategies are constantly undergoing-development alongside advances in orthopedic, oro-dental and cranio-maxillo-facial technologies and improvements in bio−/nano-materials. Indeed, there is a remarkably growing need for new oro-dental functional biomaterials that can help recreate soft and hard tissues and restore function and aesthetics of teeth/ dentition and surrounding tissues. In bone tissue engineering, HydroxyApatite minerals (HAp), the most stable CaP/Calcium Phosphate bioceramic and a widely-used material as a bone graft substitute, have been extensively studied for regenerative medicine and dentistry applications, including clinical use. Yet, limitations and challenges owing principally to its bio-mechanical strength, exist and therefore, research and innovation efforts continue to pursue enhancing its bio-effects, particularly at the nano-scale. Methods: Herein, we report on the physico-chemical properties of a novel nanoHydroxyApatite material obtained from the backbone of Salmon fish (patent-pending); an abundant and promising yet under-explored alternative HAp source. Briefly, our nanoS-HAp obtained via a modified and innovative alkaline hydrolysis–calcination process was characterized by X-ray diffraction, electron microscopy, spectroscopy, and a cell viability assay. Results and Discussion: When compared to control HAp (synthetic, human, bovine or porcine), our nanoS-HAp demonstrated attractive characteristics, a promising biomaterial candidate for use in bone tissue engineering, and beyond. | ca |
dc.format.extent | 10 | ca |
dc.language.iso | eng | ca |
dc.publisher | Frontiers Media | ca |
dc.relation.ispartof | Frontiers in Medicine | ca |
dc.relation.ispartofseries | 11 | |
dc.rights | © 2024 Muñoz, Haidar, Puigdollers, Guerra, Padilla, Ortega and García. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | ca |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject.other | Biomaterials | ca |
dc.subject.other | Hidroxiapatita | ca |
dc.subject.other | Nanotecnologia | ca |
dc.subject.other | Osteointegrativa | ca |
dc.subject.other | Osteoconducció | ca |
dc.subject.other | Ós de salmó | ca |
dc.subject.other | Bioenginyeria | ca |
dc.subject.other | Biomateriales | ca |
dc.subject.other | Hidroxiapatita | ca |
dc.subject.other | Nanotecnología | ca |
dc.subject.other | Osteointegrativa | ca |
dc.subject.other | Osteoconducción | ca |
dc.subject.other | Hueso de salmón | ca |
dc.subject.other | Bioingeniería | ca |
dc.subject.other | Biomaterials | ca |
dc.subject.other | Hydroxyapatite | ca |
dc.subject.other | Nanotechnology | ca |
dc.subject.other | Osteointegrative | ca |
dc.subject.other | Osteoconduction | ca |
dc.subject.other | Osteoinduction | ca |
dc.subject.other | Salmon bone | ca |
dc.subject.other | Bioengineering | ca |
dc.title | A novel Chilean salmon fish backbone-based nanoHydroxyApatite functional biomaterial for potential use in bone tissue engineering | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.subject.udc | 616.3 | ca |
dc.identifier.doi | https://doi.org/10.3389/fmed.2024.1330482 | ca |