Polyethylene glycol pulsed electrodeposition for the development of antifouling coatings on titanium
Author
Buxadera-Palomero, Judit
Albó, Kim
Gil Mur, Francisco Javier
Mas-Moruno, Carlos
Rodríguez, Daniel
Publication date
2020ISSN
2079-6412
Abstract
Titanium dental implants are widely used for the replacement of damaged teeth. However, bacterial infections at the interface between soft tissues and the implant can impair the functionality of the device and lead to failure. In this work, the preparation of an antifouling coating of polyethylene glycol (PEG) on titanium by pulsed electrodeposition was investigated in order to reduce Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) adhesion while maintaining human fibroblast adhesion. Different pulsed conditions were prepared and characterized by contact angle, Focused Ion Beam (FIB), Fourier Transformed Infrared Spectroscopy in the Attenuated Total Reflectance mode (ATR-FTIR), and X-ray photoelectron spectroscopy (XPS). XPS tested fibronectin adsorption. S. aureus, E. coli and human fibroblast adhesion was tested in vitro in both mono and co-culture settings. Physicochemical characterization proved useful for confirming the presence of PEG and evaluating the efficiency of the coating methods. Fibronectin adsorption decreased for all of the conditions, but an adsorption of 20% when compared to titanium was maintained, which supported fibroblast adhesion on the surfaces. In contrast, S. aureus and E. coli attachment on coated surfaces decreased up to 90% vs. control titanium. Co-culture studies with the two bacterial strains and human fibroblasts showed the efficacy of the coatings to allow for eukaryotic cell adhesion, even in the presence of pre-adhered bacteria.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
616.3 - Pathology of the digestive system. Complaints of the alimentary canal
Keywords
Implants dentals
Revestiments
Titani
Boca -- Microbiologia
Bacteris
Implantes dentales
Revestimientos
Titanio
Microbiología oral
Bacterias
Dental implants
Coatings
Titanium
Mouth -- Microbiology
Bacteria
Pages
17
Publisher
MDPI
Collection
10;5
Is part of
Coatings
Citation
Buxadera-Palomero, Judit; Albó, Kim; Gil Mur, Francisco Javier [et al.]. Polyethylene glycol pulsed electrodeposition for the development of antifouling coatings on titanium. Coatings, 2020, 10(5), p. 1-17. Disponible en: <https://www.mdpi.com/2079-6412/10/5/456>. Fecha de acceso: 3 jun. 2020. DOI: 10.3390/coatings10050456 .
Grant agreement number
info:eu-repo/grantAgreement/MINECO/MAT2015-67183-R
info:eu-repo/grantAgreement/MINECO/MAT2017-83905-R
This item appears in the following Collection(s)
- Odontologia [226]
Rights
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/