Economic evaluation of three populational screening strategies for cervical cancer in the county of Valles Occidental: CRICERVA clinical trial
Author
Acera Perez, Amèlia
Rodríguez, Ana
Trapero-Bertran, Marta
Soteras, Pilar
Sánchez, Norman
Bonet Simó, Josep Maria
Manresa, Josep Maria
Hidalgo Valls, Pablo
Torán-Monserrat, Pere
Prieto, Gemma
Publication date
2011-10-19ISSN
1472-6963
Abstract
Background: A high percentage of cervical cancer cases have not undergone cytological tests within 10 years
prior to diagnosis. Different population interventions could improve coverage in the public system, although costs
will also increase. The aim of this study was to compare the effectiveness and the costs of three types of
population interventions to increase the number of female participants in the screening programmes for cancer of
the cervix carried out by Primary Care in four basic health care areas.
Methods/Design: A cost-effectiveness analysis will be performed from the perspective of public health system
including women from 30 to 70 years of age (n = 20,994) with incorrect screening criteria from four basic health
care areas in the Valles Occidental, Barcelona, Spain. The patients will be randomly distributed into the control
group and the three intervention groups (IG1: invitation letter to participate in the screening; IG2: invitation letter
and informative leaflet; IG3: invitation letter, informative leaflet and a phone call reminder) and followed for three
years. Clinical effectiveness will be measured by the number of HPV, epithelial lesions and cancer of cervix cases
detected. The number of deaths avoided will be secondary measures of effectiveness. The temporal horizon of the
analysis will be the life expectancy of the female population in the study. Costs and effectiveness will be
discounted at 3%. In addition, univariate and multivariate sensitivity analysis will be carried out.
Discussion: IG3 is expected to be more cost-effective intervention than IG1 and IG2, with greater detection of HPV
infections, epithelial lesions and cancer than other strategies, albeit at a greater cost.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
33 - Economics. Economic science
61 - Medical sciences
Keywords
Cost effectiveness
Cost-eficàcia
Análisis coste-beneficio
Ginecologia
Gynecology
Ginecología
Pages
7
Publisher
BMC
Collection
11; 287
Is part of
BMC Health Services Research
Citation
Acera, Amelia Rodríguez, Ana Trapero Bertran, Marta; Soteras, Pilar et al. «Economic evaluation of three populational screening strategies for cervical cancer in the county of Valles Occidental: CRICERVA clinical trial». BMC Health Services Research, 2011, vol. 11, art. 287. Disponible en: <https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-11-278>. Fecha de acceso: 05 dic. 2019. DOI: 10.1186/1472-6963-11-278
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Rights
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