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Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom
(Public Library of Science, 2014)
Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The ...
Development and validation of a sample entropy-based method to identify complex patient-ventilator interactions during mechanical ventilation
(Springer Nature, 2020)
Patient-ventilator asynchronies can be detected by close monitoring of ventilator screens by clinicians or through automated algorithms. However, detecting complex patient-ventilator interactions (CP-VI), ...
Impact of the bacterial nasopharyngeal microbiota on the severity of genus enterovirus lower respiratory tract infection in children: a case–control study
(John Wiley & Sons, 2023)
Introduction: Rhinoviruses (RV) and enteroviruses (EV) are among the main causative etiologies of lower respiratory tract infection (LRTI) in children. The clinical spectrum of RV/EV infection is wide, ...
Quality of life impairment after a diagnosis of Cushing’s syndrome
(Springer Nature, 2022)
This brief review is devoted mainly to publications in the last 5 years dealing with health-related quality of life (QoL) after a diagnosis of endogenous hypercortisolism, due to pituitary-dependent ...
Blood test dynamics in hospitalized COVID-19 patients: Potential utility of D-dimer for pulmonary embolism diagnosis
(Public Library of Science, 2020-12-28)
Background: A higher incidence of thrombotic events, mainly pulmonary embolism (PE), has been reported in hospitalized patients with COVID-19. The main objective was to assess clinical and laboratory ...
Plataformas digitales y empleo: necesidad de monitorización y vigilancia de Salud Pública
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Actualmente, la relación entre las condiciones del trabajo y empleo con la salud es bien conocida, además esta relación es un importante determinante social de la salud de la población trabajadora ...
Antiretroviral therapy suppressed participants withlow CD4RT-cell counts segregate according toopposite immunological phenotypes
(Wolters Kluwer, 2016-09)
Background:The failure to increase CD4þT-cell counts in some antiretroviral therapysuppressed participants (immunodiscordance) has been related to perturbed CD4þT-cell homeostasis and impacts clinical ...
Multiple drug regimen-refractory rosai–dorfman–destombes disease mimicking relapsing polychondritis successfully treated with cobimetinib
(European Federation of Internal Medicine, 2022)
Rosai-Dorfman-Destombes disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare non-Langerhans cell histiocytosis of unknown cause. The disease often manifests as bilateral painless ...
Phakomatosis pigmentovascularis cesioflammea
(ACT Publishing, 2019)
nCPAP-induced nose skin injury is a common issue in NICUs all over the world. Damage may vary from simple hyperemia in the region of application of nasal cannulae up to complete destruction of the ...
Effect of diacutaneous fibrolysis on the muscular properties of gastrocnemius muscle
(Public Library of Science, 2020)
Diacutaneous fibrolysis is a noninvasive technique that has been shown to be effective in the treatment of musculoskeletal disorders such as shoulder pain, lateral epicondylalgia, patellofemoral pain ...