• CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity 

      Fosch, Anna; Sánchez Pizarro, David; Zagmutt, Sebastian; Reguera, Ana Cristina; Batallé, Gerard; Rodríguez-García, Maria; García-Chica, Jesus; Freire-Agulleiro, Oscar; Miralpeix, Cristina; Zizzari, Philippe; Serra, Dolors; Herrero, Laura; López, Miguel; Cota, Daniela; Rodríguez Rodríguez, Rosalía; Casals, Núria (Molecular Metabolism, 2025)
      Objectives: SF1 neurons of the ventromedial hypothalamus (VMH) play a pivotal role in regulating body weight and adiposity, particularly in response to a high-fat diet (HFD), as well as in the recovery ...
    • CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation 

      Fosch Masllovet, Anna (Fecha de defensa: 2022-09-23)
      Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an ...
    • New insights of SF1 neurons in hypothalamic regulation of obesity and diabetes 

      Fosch, Anna; Zagmutt, Sebastián; Casals i Farré, Núria; Rodríguez-Rodríguez, Rosalía (International Journal of Molecular Sciences, 2021)
      Despite the substantial role played by the hypothalamus in the regulation of energy balance and glucose homeostasis, the exact mechanisms and neuronal circuits underlying this regulation remain poorly ...