Listando por materia "Medicine"
Mostrando ítems 1-20 de 35
-
A mutation in the iron-responsive element of ALAS2 is a modifier of disease severity in a patient suffering from CLPX associated erythropoietic protoporphyria
(Haematologica, 2021)Porphyrias are a group of eight genetically distinct disorders, each resulting from a partial deficiency or gain-offunction of a specific enzyme in the heme biosynthetic pathway.1 Porphyrias are inherited ... -
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
(Nature Genetics, 2004)Inflammation influences iron balance in the whole organism. A common clinical manifestation of these changes is anemia of chronic disease (ACD; also called anemia of inflammation). Inflammation reduces ... -
Association between kidney function, nutritional status and anthropometric measures in older people: the screening for CKD among older people across Europe (SCOPE) study
(BMC Geriatrics, 2020-10-02)Background: Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory ... -
Cerebral oximetry monitoring in extremely preterm infants
(The New England Journal of Medicine, 2023)BACKGROUND: The use of cerebral oximetry monitoring in the care of extremely preterm infants is increasing. However, evidence that its use improves clinical outcomes is lacking.: METHODS: In this ... -
Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance: the screening for CKD among older people across Europe (SCOPE) study
(BMC Geriatrics, 2020-10-02)Background: Chronic kidney disease (CKD) is known to be associated with several co-occurring conditions. We aimed at exploring multimorbidity patterns associated with CKD, as well as the impact of ... -
Comparación en la adquisición y retención de competencias en soporte vital entre formación uni o interdisciplinar. Estudio cuasiexperimental
(Atención Primaria, 2020-05)Se realizó un estudio prospectivo cuasiexperimental con el objetivo de evaluar las competencias de los estudiantes de enfermería después de un curso oficial en soporte vital básico (SVB) y uso del ... -
Control of systemic iron homeostasis by the 3’ iron-responsive element of divalent metal transporter 1 in mice
(HemaSphere, 2020)Tight control of intestinal iron absorption is required to avoid both iron insufficiency and excess.1 Dietary nonheme iron is taken up by absorptive enterocytes via the apical iron transporter DMT1 ... -
COVID-19: making the best out of a forced transition to online medical teaching. A mixed methods study
(Medical Science Educator, 2021)Introduction the COVID-19 pandemic resulted in a decreed confinement in our country from March until the end of term in June 2020. This forced a transition exclusively to distance learning. The aim of ... -
Functional and clinical impact of novel Tmprss6 variants in iron-refractory iron-deficiency anemia patients and genotype–phenotype studies
(Human Mutation, 2014)Iron-refractory iron-deficiency anemia (IRIDA) is a rare autosomal-recessive disorder characterized by hypochromic microcytic anemia, low transferrin saturation, and inappropriate high levels of the ... -
Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays
(Nature Protocols, 2007)RNA-binding proteins (RBPs) frequently regulate the post-transcriptional fate of target mRNAs. To identify novel target mRNAs of RBPs, we incubate total RNA with recombinant RBP and immunoselect the ... -
Inspiratory and expiratory muscle training in subacute stroke: a randomized clinical trial
(Neurology, 2015)Objective: To assess the effectiveness, feasibility, and safety of short-term inspiratory and expiratory muscle training (IEMT) in subacute stroke patients. Methods: Within 2 weeks of stroke onset, 109 ... -
Interlimb asymmetries in youth tennis players: relationships with performance
(Journal of Strength and Conditioning Research, 2020)Madruga-Parera, M, Bishop, C, Fort-Vanmeerhaeghe, A, Beltran-Valls, MR, Gonzalo-Skok, O, and Romero-Rodríguez, D. Interlimb asymmetries in youth tennis players: relationships with performance. J Strength ... -
Iron refractory iron deficiency anemia
(Haematologica, 2013)Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6In vitro gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an ... -
Iron-regulatory proteins limit hypoxia-inducible factor 2α expression in iron deficiency
(Nature Structural & Molecular Biology, 2007)Hypoxia stimulates erythropoiesis, the major iron-utilization pathway. We report the discovery of a conserved, functional iron-responsive element (IRE) in the 5′ untranslated region of the messenger RNA ... -
Is the precautionary principle adaptable to emergency scenarios to speed up research, risking the individual informed consent?
(American Journal of Bioethics, 2013) -
La medicina en la posmodernidad
(Revista d'Humanitats, 2023)La posmodernidad se autointerpreta como una clara apuesta por el progreso mundial y se constituye como la siguiente etapa en la llamada época moderna. Como movimiento cultural y social abarca múltiples ...