Listando por materia "Cèl·lules mare cancerígenes"
Mostrando ítems 1-3 de 3
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CDKN1A/p21 in breast cancer: part of the problem, or part of the solution?
(International Journal of Molecular Sciences, 2023)Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ... -
Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
(Cancers, 2019)The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have ... -
Role of the NUDT enzymes in breast cancer
(International Journal of Molecular Sciences, 2021)Despite global research efforts, breast cancer remains the leading cause of cancer death in women worldwide. The majority of these deaths are due to metastasis occurring years after the initial treatment ...