Visualitzant per matèria "Pèptids"
Ara mostrant els elements 1-9 de 9
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All-in-one trifunctional strategy: a cell adhesive, bacteriostatic and bactericidal coating for titanium implants
(Colloids and Surfaces B: Biointerfaces, 2018-09)Strategies to inhibit initial bacterial adhesion are extremely important to prevent infection on biomaterial surfaces. However, the simultaneous attraction of desired eukaryotic cells remains a challenge ... -
Computational modeling as a tool to investigate PPI: from drug design to tissue engineering
(Frontiers in Molecular Biosciences, 2021)Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the ... -
Impedimetric antimicrobial peptide-based sensor for the early detection of periodontopathogenic bacteria
(Biosensors and Bioelectronics, 2016-12-15)Peri-implantitis, an inflammation caused by biofilm formation, constitutes a major cause of implant failure in dentistry. Thus, the detection of bacteria at the early steps of biofilm growth represents ... -
Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
(Advanced Healthcare Materials, 2015)A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa ... -
Study on the use of 3‐aminopropyltriethoxysilane and 3‐chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti–Nb–Hf alloy
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014-06-09)A biocompatible new titanium alloy Ti–16Hf–25Nb with low elastic modulus (45 GPa) and the use of short bioadhesive peptides derived from the extracellular matrix have been studied. In terms of cell ... -
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Acta Biomaterialia, 2016-10-01)Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ... -
Surface immobilization chemistry of a laminin-derived peptide affects keratinocyte activity
(Coatings, 2020)Many chemical routes have been proposed to immobilize peptides on biomedical device surfaces, and in particular, on dental implants to prevent peri-implantitis. While a number of factors affect peptide ... -
Tuning mesenchymal stem cell response onto titanium-niobium-hafnium alloy by recombinant fibronectin fragments
(ACS Applied Materials and Interfaces, 2016)Since metallic biomaterials used for bone replacement possess low bioactivity, the use of cell adhesive moieties is a common strategy to improve cellular response onto these surfaces. In recent years, ... -
Two different strategies to enhance osseointegration in porous titanium: inorganic thermo-chemical treatment versus organic coating by peptide adsorption
(International Journal of Molecular Sciences, 2018)In this study, highly-interconnected porous titanium implants were produced by powder sintering with different porous diameters and open interconnectivity. The actual foams were produced using high cost ...