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    • Antibacterial approaches in tissue engineering using metal ions and nanoparticles: from mechanisms to applications 

      Godoy Gallardo, Maria; Eckhard, Ulrich; Delgado, Luis M.; de Roo Puente, Yolanda J.D.; Hoyos Nogués, Mireia; Gil Mur, Francisco Javier; Pérez Antoñanzas, Roman (Bioactive Materials, 2021-12)
      Bacterial infection of implanted scaffolds may have fatal consequences and, in combination with the emergence of multidrug bacterial resistance, the development of advanced antibacterial biomaterials ...
    • Assessing the potential role of copper and cobalt in stimulating angiogenesis for tissue regeneration 

      Bosch Rué, Elia; Díez-Tercero, Leire; Rodríguez González, Raquel; Bosch Canals, Begoña Maria; Pérez Antoñanzas, Roman (PLoS One, 2021)
      The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations ...
    • Biological roles and delivery strategies for ions to promote osteogenic induction 

      Bosch-Rué, Elia; Diez-Tercero, Leire; Giordano-Kelhoffer, Barbara; Delgado, Luis M.; Bosch Canals, Begoña María; Hoyos Nogués, Mireia; Mateos-Timoneda, Miguel Angel; Tran, Phong A.; Gil Mur, Francisco Javier; Pérez Antoñanzas, Roman (Frontiers in Cell and Developmental Biology, 2021-01-14)
      Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ...
    • Corrosion resistance and ion release of dental prosthesis of CoCr obtained by CAD-CAM milling, casting and laser sintering 

      Padrós, Roberto; Giner-Tarrida, Luis; Herrero-Climent, Mariano; Punset fuste, Miquel; Gil, FJ (Metals, 2020)
      Corrosion resistance and ion release behavior have been evaluated for thirty dental restoration samples obtained by three different manufacturing systems: computer-aided design and manufacturing (CAD-CAM), ...
    • Ion release from dental implants, prosthetic abutments and crowns under physiological and acidic conditions 

      Arregui Gambús, María; Latour, Florian; Gil, FJ; Pérez Antoñanzas, Roman; Giner-Tarrida, Luis; Delgado, Luis M. (Coatings, 2021)
      Ion release from dental implants and prosthetic restoration can affect osteointegration and implant viability over a long period of time. Therefore, the aim of this study was to study the ion release ...
    • Modulation of macrophage response by copper and magnesium ions in combination with low concentrations of dexamethasone 

      Díez-Tercero, Leire; Delgado, Luis M.; Antoñanzas Perez, Roman (Biomedicines, 2022)
      Macrophages have been deemed crucial for correct tissue regeneration, which is a complex process with multiple overlapping phases, including inflammation. Previous studies have suggested that divalent ...
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